((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol

Base Information

Chemical Name:((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol
CAS No.:122624-77-5
Molecular Formula:C₁₀H₁₄ClN₅O
Molecular Weight:255.707
Hs Code.:
DSSTox Substance ID:DTXSID10595356
Wikidata:Q82490352
Mol file:122624-77-5.mol

Synonyms:122624-77-5;((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol;[(1R,4S)-4-[(2,5-DIAMINO-6-CHLOROPYRIMIDIN-4-YL)AMINO]CYCLOPENT-2-EN-1-YL]METHANOL;2-Cyclopentene-1-methanol, 4-[(2,5-diamino-6-chloro-4-pyrimidinyl)amino]-, (1R,4S)-rel-;{(1R,4S)-4-[(2,5-Diamino-6-chloropyrimidin-4-yl)amino]cyclopent-2-en-1-yl}methanol;SCHEMBL6691481;DTXSID10595356;AKOS022173366;(1S,4R)-4-<(2',5'-diamino-6'-chloropyrimidin-4'-yl)amino>cyclopent-2-enylmethanol;(1S,4R)-4-(2',5'-diamino-6'-chloropyrimidin-4'-yl)amino>cyclopent-2-enylmethanol;Rel-((1R,4S)-4-((2,5-diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol

Suppliers and Price of ((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol 95+%
1g
$ 1353.00

Chemenu
((1R,4S)-4-((2,5-diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol 95%
1g
$ 1274.00

BLDpharm
((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol 95+%
1g
$ 1094.00

Total 5 raw suppliers

Chemical Property of ((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol

Chemical Property:

PSA：110.08000
LogP:1.87870
Storage Temp.:2-8°C
XLogP3:0.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:255.0886878
Heavy Atom Count:17
Complexity:290

Purity/Quality:

> 95% ^*data from raw suppliers

((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C=CC1NC2=C(C(=NC(=N2)N)Cl)N)CO
Isomeric SMILES:C1[C@H](C=C[C@H]1NC2=C(C(=NC(=N2)N)Cl)N)CO

Technology Process of ((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol

There total 4 articles about ((1R,4S)-4-((2,5-Diamino-6-chloropyrimidin-4-yl)amino)cyclopent-2-en-1-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 122624-75-3
(+/-)-cis-<4-<<2-amino-6-chloro-5-<(4-chlorophenyl)azo>-4-pyrimidinyl>amino>-2-cyclopentenyl>carbinol

: 122624-77-5,896716-96-4
(+/-)-cis-<4-<(2,5-diamino-6-chloro-4-pyrimidinyl)amino>-2-cyclopentenyl>carbinol

Guidance literature:: With acetic acid; zinc; In ethanol; water; for 3h; Heating;
DOI:10.1021/jm00163a004

Reference yield:

: 229177-39-3
1-amino-4-(hydroxymethyl)-2-cyclopentene

: 122624-77-5,896716-96-4
(+/-)-cis-<4-<(2,5-diamino-6-chloro-4-pyrimidinyl)amino>-2-cyclopentenyl>carbinol

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / butan-1-ol / 48 h / Heating

2: 1.) 3 N HCl, sodium nitrite, 2.) sodium acetate trihydrate / 1.) water, 2.) acetic acid, water, RT, overnight

3: 66 percent / Zn, acetic acid / H₂O; ethanol / 3 h / Heating

With hydrogenchloride; sodium acetate; acetic acid; triethylamine; zinc; sodium nitrite; In ethanol; water; butan-1-ol;
DOI:10.1021/jm00163a004

Reference yield:

: 61865-50-7,86252-77-9
Acetic acid 4-acetylamino-cyclopent-2-enylmethyl ester

: 122624-77-5,896716-96-4
(+/-)-cis-<4-<(2,5-diamino-6-chloro-4-pyrimidinyl)amino>-2-cyclopentenyl>carbinol

Guidance literature:: Multi-step reaction with 4 steps

1: 0.5 N aq. barium hydroxide / Heating; overnight

2: Et₃N / butan-1-ol / 48 h / Heating

3: 1.) 3 N HCl, sodium nitrite, 2.) sodium acetate trihydrate / 1.) water, 2.) acetic acid, water, RT, overnight

4: 66 percent / Zn, acetic acid / H₂O; ethanol / 3 h / Heating

With hydrogenchloride; barium dihydroxide; sodium acetate; acetic acid; triethylamine; zinc; sodium nitrite; In ethanol; water; butan-1-ol;
DOI:10.1021/jm00163a004