tert-butyl N-({6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazin-2-yl}carbonyl)glycinate

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Chemical Name:tert-butyl N-({6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazin-2-yl}carbonyl)glycinate
CAS No.:1148547-20-9
Molecular Formula:C₂₅H₂₃ClF₃N₃O₄
Molecular Weight:521.924
Hs Code.:

Synonyms:tert-butyl N-({6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazin-2-yl}carbonyl)glycinate

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Chemical Property of tert-butyl N-({6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazin-2-yl}carbonyl)glycinate

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Technology Process of tert-butyl N-({6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazin-2-yl}carbonyl)glycinate

There total 1 articles about tert-butyl N-({6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazin-2-yl}carbonyl)glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1148547-19-6
6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazine-2-carboxylic acid

: 27532-96-3
glycine tert-butyl ester hydrochloride

: 1148547-20-9
tert-butyl N-({6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazin-2-yl}carbonyl)glycinate

Guidance literature:: 6-(2-chlorophenyl)-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazine-2-carboxylic acid; With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 20 ℃; for 0.833333h;

glycine tert-butyl ester hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;