Technology Process of C16H11BrO4
There total 3 articles about C16H11BrO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
C43H40N4O3;
In
tetrahydrofuran;
at -15 ℃;
stereoselective reaction;
Inert atmosphere;
DOI:10.1021/acs.joc.8b02332
- Guidance literature:
-
Multi-step reaction with 2 steps
1: acetic anhydride / 2 h / 80 °C
2: 3-[3,5-bis(trifluoromethyl)phenylamino]-4-[(S)-[6-methoxy-2-phenylquinolin-4-yl][(2S,4S,8R)-8-vinylquinuclidin-2-yl]methylamino]cyclobut-3-ene-1,2-dione; N-ethyl-N,N-diisopropylamine / tert-butyl methyl ether / 48 h / -15 °C / Inert atmosphere
With
3-[3,5-bis(trifluoromethyl)phenylamino]-4-[(S)-[6-methoxy-2-phenylquinolin-4-yl][(2S,4S,8R)-8-vinylquinuclidin-2-yl]methylamino]cyclobut-3-ene-1,2-dione; acetic anhydride; N-ethyl-N,N-diisopropylamine;
In
tert-butyl methyl ether;
DOI:10.1021/ol300453s
- Guidance literature:
-
Multi-step reaction with 2 steps
1: acetic anhydride / 2 h / 80 °C
2: C43H40N4O3 / tetrahydrofuran / -15 °C / Inert atmosphere
With
C43H40N4O3; acetic anhydride;
In
tetrahydrofuran;
DOI:10.1021/acs.joc.8b02332