Methyl 2,3-anhydro-5-O-(p-toluenesulfonyl)-α-D-ribofuranoside

Base Information

• Chemical Name: Methyl 2,3-anhydro-5-O-(p-toluenesulfonyl)-α-D-ribofuranoside
• CAS No.: 66108-06-3
• Molecular Formula: C₁₃H₁₆O₆S
• Molecular Weight: 300.332
• Mol file: 66108-06-3.mol

Synonyms:Methyl 2,3-anhydro-5-O-(p-toluenesulfonyl)-α-D-ribofuranoside

Chemical Property of Methyl 2,3-anhydro-5-O-(p-toluenesulfonyl)-α-D-ribofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 2,3-anhydro-5-O-(p-toluenesulfonyl)-α-D-ribofuranoside

There total 6 articles about Methyl 2,3-anhydro-5-O-(p-toluenesulfonyl)-α-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Methyl 3,5-O-Isopropylidene-β-D-xylofuranoside (51754-99-5) → methyl-[O5-(toluene-4-sulfonyl)-2,3-anhydro-β-D-lyxofuranoside] (66108-03-0,66108-06-3,74128-49-7,106756-76-7,108942-13-8)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine

2: aqueous acetic acid

3: sodium methylate; methanol

4: pyridine

With pyridine; methanol; sodium methylate; acetic acid;

Reference yield:

Methyl-2-O-tosyl-β-D-xylofuranosid (96622-64-9) → methyl-[O5-(toluene-4-sulfonyl)-2,3-anhydro-β-D-lyxofuranoside] (66108-03-0,66108-06-3,74128-49-7,106756-76-7,108942-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate; methanol

2: pyridine

With pyridine; methanol; sodium methylate;

Reference yield:

methyl-[O3,O5-isopropylidene-O2-(toluene-4-sulfonyl)-β-D-xylofuranoside] (551929-54-5) → methyl-[O5-(toluene-4-sulfonyl)-2,3-anhydro-β-D-lyxofuranoside] (66108-03-0,66108-06-3,74128-49-7,106756-76-7,108942-13-8)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous acetic acid

2: sodium methylate; methanol

3: pyridine

With pyridine; methanol; sodium methylate; acetic acid;

upstream raw materials:

p-toluenesulfonyl chloride

methyl 2,3-anhydro-β-D-lyxofuranoside

Methyl 3,5-O-Isopropylidene-β-D-xylofuranoside

Methyl-2-O-tosyl-β-D-xylofuranosid

Downstream raw materials:

2-deoxy-5-O-(p-toluenesulfonyl)-α-D-ribofuranoside

Toluene-4-sulfonic acid (2S,4R,5S)-4-hydroxy-5-methoxy-tetrahydro-furan-2-ylmethyl ester