[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aMinophenyl)sulfonyl]aMino] propyl]carbaMic Acid tert-Butyl Ester-d9

Base Information

Chemical Name:[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aMinophenyl)sulfonyl]aMino] propyl]carbaMic Acid tert-Butyl Ester-d9
CAS No.:1146967-63-6
Molecular Formula:C₂₅H₃₇N₃O₅S
Molecular Weight:500.58
Hs Code.:
Mol file:1146967-63-6.mol

Synonyms:tert-butyl (2S,3R)-4-(4-amino-N-(isobutyl-d9)-phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

Suppliers and Price of [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aMinophenyl)sulfonyl]aMino] propyl]carbaMic Acid tert-Butyl Ester-d9

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aminophenyl)sulfonyl]amino]propyl]carbamicAcidtert-ButylEster-d9
5mg
$ 580.00

Medical Isotopes, Inc.
[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aminophenyl)sulfonyl]amino]propyl]carbamicAcidtert-ButylEster-d9
10 mg
$ 1425.00

Total 1 raw suppliers

Chemical Property of [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aMinophenyl)sulfonyl]aMino] propyl]carbaMic Acid tert-Butyl Ester-d9

Chemical Property:

Solubility.:DCM, Methanol

Purity/Quality:

>98% ^*data from raw suppliers

[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aminophenyl)sulfonyl]amino]propyl]carbamicAcidtert-ButylEster-d9 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Isotope labelled Darunavir (D193500) intermediate, a potent inhibitor of HIV-1 protease.

Technology Process of [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aMinophenyl)sulfonyl]aMino] propyl]carbaMic Acid tert-Butyl Ester-d9

There total 1 articles about [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aMinophenyl)sulfonyl]aMino] propyl]carbaMic Acid tert-Butyl Ester-d9 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1146967-62-5
tert-butyl (2S,3R)-3-hydroxy-4-(N-(isobutyl-d9)-4-nitrophenylsulfonamido)-1-phenylbutan-2-ylcarbamate

: 1146967-63-6
tert-butyl (2S,3R)-4-(4-amino-N-(isobutyl-d9)-phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

Guidance literature:: With hydrogen; palladium on carbon; In methanol; water; ethyl acetate; for 2.5h; under 2068.65 Torr;

Reference yield: 96.0%

: 1146967-63-6
tert-butyl (2S,3R)-4-(4-amino-N-(isobutyl-d9)-phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate

: 1146967-60-3
4-amino-N-((2S,3R))-3-amino-2-hydroxy-4-phenylbutyl-N-(isobutyl-d9)-benzenesulfonamide

Guidance literature:: tert-butyl (2S,3R)-4-(4-amino-N-(isobutyl-d9)-phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate; With hydrogenchloride; In 1,4-dioxane; methanol; dichloromethane; at 20 ℃; for 3h;

With sodium hydroxide; In dichloromethane; water; pH=12;