Technology Process of C43H55FN4O7
There total 17 articles about C43H55FN4O7 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: toluene-4-sulfonic acid / 20 °C / Inert atmosphere
2: pyridine; triethylamine / dichloromethane / 20 °C / Inert atmosphere
3: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere
4: propylamine; 3-mercaptopropionic acid / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
5: N,N-diethyl-N-isopropylamine; HATU / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere
With
pyridine; propylamine; N,N-diethyl-N-isopropylamine; di-isopropyl azodicarboxylate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; HATU; 3-mercaptopropionic acid;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Inert atmosphere; Reflux
2: N,N-diethyl-N-isopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere
3: hydrogenchloride / ethyl acetate / 20 °C / Inert atmosphere
4: N,N-diethyl-N-isopropylamine; HATU / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere
With
hydrogenchloride; N,N-diethyl-N-isopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole; HATU;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 6 steps
1: potassium carbonate / methanol / 1 h / 20 °C / Inert atmosphere
2: copper(l) iodide; bis(benzonitrile)palladium(II) chloride; tri-tert-butyl phosphine; diisopropylamine / 1,4-dioxane; hexane / 70 °C / Inert atmosphere
3: platinum(IV) oxide; hydrogen / ethanol; ethyl acetate / 20 °C / Inert atmosphere
4: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere
5: propylamine; 3-mercaptopropionic acid / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
6: N,N-diethyl-N-isopropylamine; HATU / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere
With
propylamine; platinum(IV) oxide; copper(l) iodide; bis(benzonitrile)palladium(II) chloride; N,N-diethyl-N-isopropylamine; tri-tert-butyl phosphine; di-isopropyl azodicarboxylate; hydrogen; potassium carbonate; diisopropylamine; triphenylphosphine; HATU; 3-mercaptopropionic acid;
In
tetrahydrofuran; 1,4-dioxane; methanol; ethanol; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm2007062