C₁₉H₂₅ClHgO₅

Base Information

• Chemical Name: C₁₉H₂₅ClHgO₅
• CAS No.: 909576-50-7
• Molecular Formula: C₁₉H₂₅ClHgO₅
• Molecular Weight: 569.447
• Mol file: 909576-50-7.mol

Synonyms:C₁₉H₂₅ClHgO₅

Chemical Property of C₁₉H₂₅ClHgO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₅ClHgO₅

There total 1 articles about C₁₉H₂₅ClHgO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(1S)-1-((3aR,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)pent-4-en-1-ol (209849-12-7) → C19H25ClHgO5 (909576-50-7)

Guidance literature:

With mercury(II) diacetate; In tetrahydrofuran; at 20 ℃; for 2h; diastereoselective reaction;

DOI:10.1007/s11164-012-0702-y

Reference yield: 81.0%

C19H25ClHgO5 (909576-50-7) → C19H26O6 (909576-58-5)

Guidance literature:

With sodium tetrahydroborate; oxygen; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1007/s11164-012-0702-y

Reference yield:

C19H25ClHgO5 (909576-50-7) → C23H38O5Si (1391825-73-2)

Guidance literature:

Multi-step reaction with 9 steps

1.1: oxygen; sodium tetrahydroborate / N,N-dimethyl-formamide / 4 h / 20 °C

2.1: sodium; naphthalene / tetrahydrofuran / 0 °C

3.1: sodium hydride / 3 h / 20 °C

4.1: sodium hydride; carbon disulfide; methyl iodide / tetrahydrofuran / 2 h / 0 °C

4.2: 3 h / 90 °C

5.1: toluene-4-sulfonic acid / tetrahydrofuran; water / 2 h / 60 °C

5.2: 10 h / 0 - 20 °C

6.1: tetrahydrofuran / 10 h / 0 - 20 °C

7.1: dmap / dichloromethane / 2 h / 20 °C

8.1: mercury(II) diacetate / tetrahydrofuran / 2 h / 20 °C

9.1: oxygen; sodium tetrahydroborate / N,N-dimethyl-formamide / 4 h / 20 °C

With carbon disulfide; dmap; sodium tetrahydroborate; naphthalene; mercury(II) diacetate; oxygen; sodium; sodium hydride; toluene-4-sulfonic acid; methyl iodide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; 4.1: |Barton-McCombie Deoxygenation / 4.2: |Barton-McCombie Deoxygenation;

DOI:10.1007/s11164-012-0702-y

upstream raw materials:

(1S)-1-((3aR,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)pent-4-en-1-ol

Downstream raw materials:

C₂₃H₃₈O₅Si

C₁₉H₂₆O₅

C₁₉H₂₆O₆

C₁₉H₂₆O₆