(R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester

Base Information

Chemical Name:(R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester
CAS No.:1082831-76-2
Molecular Formula:C₂₀H₂₂ClN₃O₃
Molecular Weight:387.866
Hs Code.:

Synonyms:(R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester

Suppliers and Price of (R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester

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Chemical Property of (R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester

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Technology Process of (R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester

There total 2 articles about (R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₂₁ClN₂O₂

: 530-62-1
1,1'-carbonyldiimidazole

: 1082831-76-2
(R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester

Guidance literature:: C₁₉H₂₁ClN₂O₂; 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 1h;

With ammonium hydroxide; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield:

: 38212-33-8
4-(4-chlorophenyl) piperazine

: 2768-42-5,40620-59-5
(R)-3-phenyl-3-hydroxypropionic acid

: 1082831-76-2
(R)-carbamic acid 3-[4-(4-chloro-phenyl)-piperazine-1-yl]-3-oxo-1-phenyl-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / tetrahydrofuran / 5 h / 25 °C

2.1: tetrahydrofuran / 1 h / 20 °C

2.2: 2 h / 20 °C

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In tetrahydrofuran;