3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

Base Information

Chemical Name:3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate
CAS No.:136933-24-9
Molecular Formula:C₂₃H₃₃NO₁₀
Molecular Weight:483.516
Hs Code.:

Synonyms:3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

Suppliers and Price of 3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

There total 10 articles about 3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 136933-20-5
4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octose propane-1,3-diyl acetal

: 136933-24-9
3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

Guidance literature:: With ozone; In ethyl acetate; at -40 ℃; for 0.0833333h;
DOI:10.1016/0008-6215(92)84183-S

Reference yield:

: 69891-92-5
2-(1,3-dioxan-2-yl)ethyltriphenylphosphonium bromide

: 136933-24-9
3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

Guidance literature:: Multi-step reaction with 8 steps

1: 1) KOtBu / 1) THF, r.t., 30 min, 2) 10 min

2: 94 percent / acetonitrile / 2 h / -20 °C

3: 84 percent / 3-chloroperoxybenzoic acid / CH₂Cl₂ / 12.3 h / 0 °C

4: 86 percent / KH / CH₂Cl₂ / 10 h

5: 87 percent / BF₃*Et₂O / CH₂Cl₂ / 0.33 h / 0 °C

6: 91 percent / p-TsOH*H₂O / pyridine; H₂O / 12 h / 80 °C

7: 89 percent / Bu₃SnH, AIBN / benzene / 1 h / Heating

8: 74 percent / O₃ / ethyl acetate / 0.08 h / -40 °C

With 2,2'-azobis(isobutyronitrile); potassium tert-butylate; tri-n-butyl-tin hydride; potassium hydride; toluene-4-sulfonic acid; ozone; 3-chloro-benzenecarboperoxoic acid; boron trifluoride diethyl etherate; In pyridine; dichloromethane; water; ethyl acetate; acetonitrile; benzene;
DOI:10.1016/0008-6215(92)84183-S

Reference yield:

: 58645-35-5,58645-40-2,144216-75-1
3,4-O-isopropylidene-D-arabinopyranose

: 136933-24-9
3-hydroxypropyl 4-acetamido-8-O-benzoyl-2,4-dideoxy-6,7-O-isopropylidene-D-glycero-D-galacto-octonate

Guidance literature:: Multi-step reaction with 8 steps

1: 1) KOtBu / 1) THF, r.t., 30 min, 2) 10 min

2: 94 percent / acetonitrile / 2 h / -20 °C

3: 84 percent / 3-chloroperoxybenzoic acid / CH₂Cl₂ / 12.3 h / 0 °C

4: 86 percent / KH / CH₂Cl₂ / 10 h

5: 87 percent / BF₃*Et₂O / CH₂Cl₂ / 0.33 h / 0 °C

6: 91 percent / p-TsOH*H₂O / pyridine; H₂O / 12 h / 80 °C

7: 89 percent / Bu₃SnH, AIBN / benzene / 1 h / Heating

8: 74 percent / O₃ / ethyl acetate / 0.08 h / -40 °C

With 2,2'-azobis(isobutyronitrile); potassium tert-butylate; tri-n-butyl-tin hydride; potassium hydride; toluene-4-sulfonic acid; ozone; 3-chloro-benzenecarboperoxoic acid; boron trifluoride diethyl etherate; In pyridine; dichloromethane; water; ethyl acetate; acetonitrile; benzene;
DOI:10.1016/0008-6215(92)84183-S