Carbamic acid, (5-amino-1H-pyrazol-3-yl)-, 1,1-dimethylethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, (5-amino-1H-pyrazol-3-yl)-, 1,1-dimethylethyl ester (9CI)
• CAS No.: 123363-50-8
• Molecular Formula: C8H14 N4 O2
• Molecular Weight: 198.225
• Mol file: 123363-50-8.mol

Synonyms:Carbamicacid, (5-amino-1H-pyrazol-3-yl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property of Carbamic acid, (5-amino-1H-pyrazol-3-yl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

• PSA: 93.03000
• LogP: 1.99310

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic acid, (5-amino-1H-pyrazol-3-yl)-, 1,1-dimethylethyl ester (9CI)

There total 2 articles about Carbamic acid, (5-amino-1H-pyrazol-3-yl)-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(5-nitro-2H-pyrazol-3-yl)-carbamic acid tert-butyl ester (937040-09-0) → tert-butyl 3-amino-1H-pyrazol-5-ylcarbamate (123363-50-8)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol;

Reference yield: 96.0%

tert-butyl (5-nitro-1H-pyrazol-3-yl)carbamate (937040-09-0) → tert-butyl (5-amino-1H-pyrazol-3-yl)carbamate (123363-50-8,1290181-43-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; for 24h; Inert atmosphere;

Reference yield: 68.0%

malondialdehyde bis(diethyl acetal) (122-31-6) + tert-butyl (5-amino-1H-pyrazol-3-yl)carbamate (123363-50-8,1290181-43-9) → tert-butyl pyrazolo[1,5-a]pyrimidin-2-ylcarbamate (1394003-94-1)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 20 ℃;

upstream raw materials:

(5-nitro-2H-pyrazol-3-yl)-carbamic acid tert-butyl ester

tert-butyl (5-nitro-1H-pyrazol-3-yl)carbamate

Downstream raw materials:

{5-[3-(3-acetyl-phenyl)-thioureido]-1H-pyrazol-3-yl}-carbamic acid tert-butyl ester

1-amino-5-(3,5-difluorophenyl)-7-ethyl-3H-pyrazolo[3,4-c][2,7]naphthyridin-6(7H)-one

tert-butyl 4-(4-(3-(tert-butoxycarbonylamino)-5-cyano-6-(2-fluoro-4-methoxyphenyl)-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-yl)phenyl)piperazine-1-carboxylate

tert-butyl 4-(4-(3-(tert-butoxycarbonylamino)-5-cyano-6-(2-fluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)piperazine-1-carboxylate