[(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate)

Base Information

• Chemical Name: [(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate)
• CAS No.: 339531-12-3
• Molecular Formula: C₆₆H₇₂O₈
• Molecular Weight: 993.293
• Mol file: 339531-12-3.mol

Synonyms:[(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate)

Chemical Property of [(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate)

There total 2 articles about [(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

[(E)-1,6-bis(triisopropylsilyl)hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate) (339531-10-1) → [(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate) (339531-12-3)

Guidance literature:

With tetrabutyl ammonium fluoride; water; In tetrahydrofuran; for 1h;

DOI:10.1039/a801269e

Reference yield:

(E)-2-((triisopropylsilyl)ethynyl)-3-((trimethylsilyl)ethynyl)but-2-ene-1,4-diol (168009-23-2) → [(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate) (339531-12-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / Bu₃P; TMAD / tetrahydrofuran / 24 h / 60 °C

2: 99 percent / Bu₄NF / tetrahydrofuran / 1 h / 20 °C

With tributylphosphine; diamide; tetrabutyl ammonium fluoride; In tetrahydrofuran; 1: Mitsunobu reaction;

DOI:10.1002/1522-2675(20010228)84:2<296::AID-HLCA296>3.0.CO;2-X

Reference yield: 17.0%

phenylacetylene (536-74-3) + [(E)-hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate) (339531-12-3) → [(5E,11E)-1,16-diphenylhexadeca-5,11-diene-1,3,7,9,13,15-hexayne-5,6,11,12-tetrayl]tetramethylene tetrakis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate) + [(E)-1,10-diphenyldec-5-ene-1,3,7,9-tetrayne-5,6-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}-benzoate)

Guidance literature:

With air; N,N,N,N,-tetramethylethylenediamine; copper(l) chloride; In dichloromethane; at 25 ℃; for 2h;

DOI:10.1039/a801269e

upstream raw materials:

[(E)-1,6-bis(triisopropylsilyl)hex-3-ene-1,5-diyne-3,4-diyl]dimethylene bis(3,5-bis{[4-(tert-butyl)benzyl]oxy}benzoate)

(E)-2-((triisopropylsilyl)ethynyl)-3-((trimethylsilyl)ethynyl)but-2-ene-1,4-diol