trans-1-iodo-4-methoxycyclohexane

Base Information

• Chemical Name: trans-1-iodo-4-methoxycyclohexane
• CAS No.: 1417720-81-0
• Molecular Formula: C₇H₁₃IO
• Molecular Weight: 240.084
• Mol file: 1417720-81-0.mol

Synonyms:trans-1-iodo-4-methoxycyclohexane

Chemical Property of trans-1-iodo-4-methoxycyclohexane

Chemical Property:

Purity/Quality:

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Technology Process of trans-1-iodo-4-methoxycyclohexane

There total 1 articles about trans-1-iodo-4-methoxycyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

cis-4-methoxycyclohexanol (22188-02-9) → trans-1-iodo-4-methoxycyclohexane (1417720-81-0)

Guidance literature:

With 1-methyl-1H-imidazole; iodine; triphenylphosphine; In dichloromethane; at 0 ℃; for 15h; Schlenk technique; Inert atmosphere;

DOI:10.1002/chem.201204076

Reference yield: 83.0%

dibutyl disulfide (629-45-8) + trans-1-iodo-4-methoxycyclohexane (1417720-81-0) → butyl(trans-4-methoxycyclohexyl)sulfane (1441777-39-4)

Guidance literature:

trans-1-iodo-4-methoxycyclohexane; With tert.-butyl lithium; In diethyl ether; hexane; at -100 ℃; Schlenk technique; Inert atmosphere;

dibutyl disulfide; In diethyl ether; hexane; at -100 ℃; for 0.0833333h; stereospecific reaction; Schlenk technique; Inert atmosphere;

DOI:10.1002/chem.201204076

upstream raw materials:

cis-4-methoxycyclohexanol

Downstream raw materials:

butyl(trans-4-methoxycyclohexyl)sulfane