ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate

Base Information

• Chemical Name: ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate
• CAS No.: 787576-76-5
• Molecular Formula: C₅₄H₄₅NO₂
• Molecular Weight: 739.957
• Mol file: 787576-76-5.mol

Synonyms:ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate

Chemical Property of ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate

There total 1 articles about ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

4-biphenylboronic acid (5122-94-1) + ethyl N-(2,6-dibromo-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate (787576-86-7) → ethyl N-(2-bromo-4-phenyl-6-biphenyl-4-ylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate + ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate (787576-76-5)

Guidance literature:

With palladium diacetate; potassium fluoride; johnphos; In toluene; for 24h; Heating;

DOI:10.1021/ja047738r

Reference yield:

ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate (787576-76-5) → (2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)diazomethane

Guidance literature:

Multi-step reaction with 2 steps

1: NaNO₂; Ac₂O / acetic acid / 1 h / 20 °C

2: t-BuOK / tetrahydrofuran / 24 h / 20 °C

With potassium tert-butylate; acetic anhydride; sodium nitrite; In tetrahydrofuran; acetic acid;

DOI:10.1021/ja047738r

Reference yield:

ethyl N-(2,6-bisbiphenyl-4-yl-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate (787576-76-5) → 1-biphenylyl-3,7-diphenyl-9-(2,6-dimethyl-4-phenylphenyl)fluorene

Guidance literature:

Multi-step reaction with 3 steps

1: NaNO₂; Ac₂O / acetic acid / 1 h / 20 °C

2: t-BuOK / tetrahydrofuran / 24 h / 20 °C

3: 82 percent / benzene / Irradiation

With potassium tert-butylate; acetic anhydride; sodium nitrite; In tetrahydrofuran; acetic acid; benzene;

DOI:10.1021/ja047738r

upstream raw materials:

4-biphenylboronic acid

ethyl N-(2,6-dibromo-4-phenylphenyl)(2,6-dimethyl-4-phenylphenyl)methylcarbamate