dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester

Base Information

• Chemical Name: dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester
• CAS No.: 476199-18-5
• Molecular Formula: C₁₁H₁₃NO₃S
• Molecular Weight: 239.295
• Mol file: 476199-18-5.mol

Synonyms:dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester

Chemical Property of dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester

There total 2 articles about dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-Hydroxy-4-methoxybenzaldehyde (673-22-3) + N,N-Dimethylcarbamoyl chloride (79-44-7) → dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester (476199-18-5)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; for 0.416667h;

Reference yield: 72.0%

2-Hydroxy-4-methoxybenzaldehyde (673-22-3) + N,N-Dimethylthiocarbamoyl chloride (16420-13-6) → dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester (476199-18-5)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In N,N-dimethyl-formamide; at 50 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.bmc.2010.05.068

Reference yield: 92.0%

dimethylthiocarbamic acid O-(2-formyl-5-methoxyphenyl) ester (476199-18-5) → dimethylthiocarbamic acid S-(2-formyl-5-methoxyphenyl) ester (476199-19-6)

Guidance literature:

at 170 ℃; for 0.2h; Microwave irradiation;

DOI:10.1016/j.bmc.2010.05.068

upstream raw materials:

2-Hydroxy-4-methoxybenzaldehyde

N,N-Dimethylcarbamoyl chloride

N,N-Dimethylthiocarbamoyl chloride

Downstream raw materials:

dimethylthiocarbamic acid S-(2-formyl-5-methoxyphenyl) ester

2-cyano-6-methoxybenzothiophene

6-hydroxy-2-cyanobenzothiophene

2-mercapto-4-methoxybenzaldehyde