3,5-Difluoro-2-(trifluoromethyl)aniline

Base Information

Chemical Name:3,5-Difluoro-2-(trifluoromethyl)aniline
CAS No.:123973-33-1
Molecular Formula:C7H4 F5 N
Molecular Weight:197.107
Hs Code.:2921420090
DSSTox Substance ID:DTXSID30382644
Wikidata:Q82173993
Mol file:123973-33-1.mol

Synonyms:3,5-difluoro-2-(trifluoromethyl)aniline;123973-33-1;2-amino-4,6-difluorobenzotrifluoride;3,5-Difluoro-2-trifluoromethyl-phenylamine;MFCD04972831;SCHEMBL3460459;DTXSID30382644;a,a,a,3,5-Pentafluoro-o-toluidine;BBL101737;STL555534;6-Amino-2,4-difluorobenzotrifluoride;2-amino-4,6-difluoro-benzotrifluoride;2-trifluoromethyI-3,5-difluoroaniline;AKOS005254342;PS-8255;3,5-difluoro-2-trifluoromethyl-aniline;3,5-Difluoro-2-(trifluoromethyl)benzenamine;FT-0643019;3,5-bis(fluoranyl)-2-(trifluoromethyl)aniline;A805179

Suppliers and Price of 3,5-Difluoro-2-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-4,6-difluorobenzotrifluoride
100mg
$ 60.00

SynQuest Laboratories
2-Amino-4,6-difluorobenzotrifluoride 98%
1 g
$ 221.00

Crysdot
3,5-Difluoro-2-(trifluoromethyl)aniline 95+%
5g
$ 501.00

CHESS?
SG000434:3,5-Difluoro-2-trifluoromethyl-phenylamine 98
1 g
$ 420.00

Chemenu
3,5-difluoro-2-(trifluoromethyl)aniline 95%
5g
$ 473.00

Biosynth Carbosynth
3,5-Difluoro-2-(Trifluoromethyl)Aniline
500 mg
$ 175.00

Biosynth Carbosynth
3,5-Difluoro-2-(Trifluoromethyl)Aniline
250 mg
$ 100.00

Biosynth Carbosynth
3,5-Difluoro-2-(Trifluoromethyl)Aniline
100 mg
$ 60.00

Biosynth Carbosynth
3,5-Difluoro-2-(Trifluoromethyl)Aniline
2 g
$ 400.00

Biosynth Carbosynth
3,5-Difluoro-2-(Trifluoromethyl)Aniline
1 g
$ 250.00

Total 18 raw suppliers

Chemical Property of 3,5-Difluoro-2-(trifluoromethyl)aniline

Chemical Property:

Vapor Pressure:0.5mmHg at 25°C
Refractive Index:1.443
Boiling Point:192°Cat760mmHg
Flash Point:79.1°C
PSA：26.02000
Density:1.474g/cm³
LogP:3.14700
Storage Temp.:2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:197.02638994
Heavy Atom Count:13
Complexity:180

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-4,6-difluorobenzotrifluoride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1N)C(F)(F)F)F)F
Uses 2-Amino-4,6-difluorobenzotrifluoride is used as a reactant in the preparation of substituted 4-phenylpiperidines for treating disease characterized by excessive lipofuscin accumulation in the retina.

Technology Process of 3,5-Difluoro-2-(trifluoromethyl)aniline

There total 1 articles about 3,5-Difluoro-2-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2,4,6-trifluoro-1-(trifluoromethyl)benzene

: 123973-33-1
3,5-difluoro-2-(trifluoromethyl)aniline

Guidance literature:: With ammonia; In tetrahydrofuran;

Reference yield: 68.0%

: 123973-33-1
3,5-difluoro-2-(trifluoromethyl)aniline

: 1-bromo-3,5-difluoro-2-(trifluoromethyl)benzene

Guidance literature:: 3,5-difluoro-2-(trifluoromethyl)aniline; With hydrogen bromide; sodium nitrite; In water; at -5 ℃; for 1h;

With copper(I) bromide; In water; at -5 - 20 ℃; for 4h;

Reference yield: 62.0%

: 123973-33-1
3,5-difluoro-2-(trifluoromethyl)aniline

: 1188412-33-0
1,5-difluoro-3-iodo-2-(trifluoromethyl)benzene

Guidance literature:: 3,5-difluoro-2-(trifluoromethyl)aniline; With nitrosonium tetrafluoroborate; In acetonitrile; at -20 - 0 ℃;

With potassium iodide; In water; acetonitrile; Cooling with ice;