bis[(N,N-dimethyl)carbamoyloxymethyl] 2',3'-dideoxyuridine 5'-monophosphate

Base Information

• Chemical Name: bis[(N,N-dimethyl)carbamoyloxymethyl] 2',3'-dideoxyuridine 5'-monophosphate
• CAS No.: 220706-69-4
• Molecular Formula: C₁₇H₂₇N₄O₁₁P
• Molecular Weight: 494.395
• Mol file: 220706-69-4.mol

Synonyms:bis[(N,N-dimethyl)carbamoyloxymethyl] 2',3'-dideoxyuridine 5'-monophosphate

Chemical Property of bis[(N,N-dimethyl)carbamoyloxymethyl] 2',3'-dideoxyuridine 5'-monophosphate

Chemical Property:

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Technology Process of bis[(N,N-dimethyl)carbamoyloxymethyl] 2',3'-dideoxyuridine 5'-monophosphate

There total 1 articles about bis[(N,N-dimethyl)carbamoyloxymethyl] 2',3'-dideoxyuridine 5'-monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2',3'-Dideoxyuridine (5983-09-5,153547-98-9) + bis[(N,N-dimethyl)carbamoyloxymethyl] hydrogen phosphate → bis[(N,N-dimethyl)carbamoyloxymethyl] 2',3'-dideoxyuridine 5'-monophosphate (220706-69-4)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In N,N-dimethyl acetamide; at 60 ℃;

DOI:10.1016/S0040-4039(98)02446-0

upstream raw materials:

2',3'-Dideoxyuridine