3-Amino-3-[2-(benzyloxy)phenyl]propanoic acid

Base Information

Chemical Name:3-Amino-3-[2-(benzyloxy)phenyl]propanoic acid
CAS No.:124082-16-2
Molecular Formula:C₁₆H₁₇NO₃
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID90697266
Mol file:124082-16-2.mol

Synonyms:124082-16-2;3-AMINO-3-[2-(BENZYLOXY)PHENYL]PROPANOIC ACID;3-amino-3-(2-phenylmethoxyphenyl)propanoic acid;3-AMINO-3-(2-BENZYLOXY-PHENYL)-PROPIONIC ACID;DTXSID90697266;3-AMINO-3-(2-BENZYLOXY-PHENYL)-PROPIONICACID

Suppliers and Price of 3-Amino-3-[2-(benzyloxy)phenyl]propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-AMINO-3-(2-BENZYLOXYPHENYL)-PROPIONIC ACID 95.00%
5MG
$ 498.29

Total 4 raw suppliers

Chemical Property of 3-Amino-3-[2-(benzyloxy)phenyl]propanoic acid

Chemical Property:

PSA：72.55000
LogP:3.44040
XLogP3:-0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:302

Purity/Quality:

98%Min ^*data from raw suppliers

3-AMINO-3-(2-BENZYLOXYPHENYL)-PROPIONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC=CC=C2C(CC(=O)O)N

Technology Process of 3-Amino-3-[2-(benzyloxy)phenyl]propanoic acid

There total 4 articles about 3-Amino-3-[2-(benzyloxy)phenyl]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 141-82-2
malonic acid

: 5896-17-3
2-(phenylmethoxy)benzaldehyde

: 124082-16-2
3-Amino-3-(2-benzyloxy-phenyl)-propionic acid

: 113982-23-3
(E)-3-[2-(benzyloxy)phenyl]acrylic acid

Guidance literature:: With ammonium acetate; In butan-1-ol; Heating;
DOI:10.1007/s11176-005-0377-9

Reference yield: 26.0%

: 141-82-2
malonic acid

: 5896-17-3
2-(phenylmethoxy)benzaldehyde

: 124082-16-2
3-Amino-3-(2-benzyloxy-phenyl)-propionic acid

Guidance literature:: With ammonium acetate;

Reference yield:

: 89-95-2
2-methyl-benzyl alcohol

: 124082-16-2
3-Amino-3-(2-benzyloxy-phenyl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: anhydrous potash / dimethylformamide / 2 h / 110 °C

2: 26 percent / ammonium acetate / butan-1-ol / Heating

With ammonium acetate; potassium carbonate; In N,N-dimethyl-formamide; butan-1-ol; 2: Rodionov reaction;
DOI:10.1007/s11176-005-0377-9