Cyclopropanecarboxaldehyde, 3-acetyl-2,2-dimethyl-, (1R-cis)- (9CI)

Base Information

Chemical Name:Cyclopropanecarboxaldehyde, 3-acetyl-2,2-dimethyl-, (1R-cis)- (9CI)
CAS No.:124150-82-9
Molecular Formula:C₈H₁₂O₂
Molecular Weight:140.182
Hs Code.:
Mol file:124150-82-9.mol

Synonyms:Cyclopropanecarboxaldehyde, 3-acetyl-2,2-dimethyl-, (1R-cis)- (9CI)

Suppliers and Price of Cyclopropanecarboxaldehyde, 3-acetyl-2,2-dimethyl-, (1R-cis)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Cyclopropanecarboxaldehyde, 3-acetyl-2,2-dimethyl-, (1R-cis)- (9CI)

Chemical Property:

PSA：34.14000
LogP:1.04650

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Cyclopropanecarboxaldehyde, 3-acetyl-2,2-dimethyl-, (1R-cis)- (9CI)

There total 6 articles about Cyclopropanecarboxaldehyde, 3-acetyl-2,2-dimethyl-, (1R-cis)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124062-50-6
(1aS,1bR,4S,5aR)-4-tert-Butyl-1,1,1b-trimethyl-hexahydro-2-oxa-4a-aza-cyclopropa[a]pentalen-5-ol

: 124150-82-9
(1R,3S)-3-Acetyl-2,2-dimethyl-cyclopropanecarbaldehyde

Guidance literature:: With tetrabutylammonium dihydrogen phosphate; In dichloromethane; for 96h; Ambient temperature;
DOI:10.1016/S0040-4020(01)85604-0

Reference yield:

: 124062-47-1
(3S,7aR)-3-tert-Butyl-7a-methyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one

: 124150-82-9
(1R,3S)-3-Acetyl-2,2-dimethyl-cyclopropanecarbaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 1) LDA, PhSeBr; 2) hydrogen peroxide / 1) -78 deg C, THF, 4 h;

2: 1) Et₂O, 25 deg C, 19 h; 2) UV lamp irradiation, 4 h

3: 0.7 eq. RED-Al / tetrahydrofuran / 25 °C

4: tetrabutyl ammonium dihydrogen phosphate / CH₂Cl₂; H₂O / 96 h / 25 °C

With Phenylselenyl bromide; dihydrogen peroxide; tetrabutylammonium dihydrogen phosphate; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/S0040-4039(00)99569-8

Reference yield:

: 124062-48-2
(3S,7aR)-3-tert-Butyl-7a-methyl-2,3-dihydro-7aH-pyrrolo[2,1-b]oxazol-5-one

: 124150-82-9
(1R,3S)-3-Acetyl-2,2-dimethyl-cyclopropanecarbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Et₂O, 25 deg C, 19 h; 2) UV lamp irradiation, 4 h

2: 0.7 eq. RED-Al / tetrahydrofuran / 25 °C

3: tetrabutyl ammonium dihydrogen phosphate / CH₂Cl₂; H₂O / 96 h / 25 °C

With tetrabutylammonium dihydrogen phosphate; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/S0040-4039(00)99569-8