2-(1,4-Dioxa-spiro[4.5]dec-8-YL)-ethylamine

Base Information

Chemical Name:2-(1,4-Dioxa-spiro[4.5]dec-8-YL)-ethylamine
CAS No.:124499-34-9
Molecular Formula:C10H19 N O2
Molecular Weight:185.26
Hs Code.:2932999099
European Community (EC) Number:808-836-5
DSSTox Substance ID:DTXSID10434857
Mol file:124499-34-9.mol

Synonyms:124499-34-9;2-(1,4-dioxaspiro[4.5]decan-8-yl)ethanamine;2-(1,4-DIOXA-SPIRO[4.5]DEC-8-YL)-ETHYLAMINE;1,4-Dioxaspiro[4.5]decane-8-ethanamine;MFCD04114534;2-(1,4-Dioxa-spiro[45]dec-8-yl)ethylamine;2-{1,4-dioxaspiro[4.5]decan-8-yl}ethan-1-amine;2-(1,4-DIOXASPIRO[4.5]DECAN-8-YL)ETHAN-1-AMINE;2-(1,4-DIOXA-SPIRO[4.5]DEC-8-YL)ethylamine;SCHEMBL1192952;DTXSID10434857;SSPKQTFXNGPRNV-UHFFFAOYSA-N;AKOS006295152;AB18527;CS-W003170;AC-29323;AS-30199;SY020598;AM20120534;EN300-3052113;A890502;2-(1,4-Dioxa-spiro[4 middot 5]dec-8-yl)ethylamine;2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine, AldrichCPR

Suppliers and Price of 2-(1,4-Dioxa-spiro[4.5]dec-8-YL)-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine
25mg
$ 75.00

TRC
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine
100mg
$ 185.00

Matrix Scientific
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 97%
5g
$ 2700.00

Matrix Scientific
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 97%
10g
$ 4500.00

J&W Pharmlab
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 95%
250mg
$ 125.00

J&W Pharmlab
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 95%
100mg
$ 109.00

J&W Pharmlab
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 95%
50mg
$ 98.00

J&W Pharmlab
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 95%
500mg
$ 149.00

J&W Pharmlab
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 95%
1g
$ 198.00

J&W Pharmlab
2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine 95%
5g
$ 798.00

Total 29 raw suppliers

Chemical Property of 2-(1,4-Dioxa-spiro[4.5]dec-8-YL)-ethylamine

Chemical Property:

PSA：44.48000
LogP:1.96880
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:185.141578849
Heavy Atom Count:13
Complexity:156

Purity/Quality:

99%, ^*data from raw suppliers

2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCC1CCN)OCCO2

Technology Process of 2-(1,4-Dioxa-spiro[4.5]dec-8-YL)-ethylamine

There total 5 articles about 2-(1,4-Dioxa-spiro[4.5]dec-8-YL)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124499-37-2
1,4-dioxaspiro[4.5]dec-8-yl acetonitrile

: 124499-34-9
1,4-dioxaspiro<4.5>decane-8-ethanamine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 2h; Yield given; Ambient temperature;
DOI:10.1021/jm00058a004

Reference yield:

: 23521-81-5,17159-82-9
(1,4-dioxaspiro[4.5]dec-8-yl)methanol

: 124499-34-9
1,4-dioxaspiro<4.5>decane-8-ethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 2 h / 0 °C

2: dimethylsulfoxide / 3 h / Heating

3: LAH / diethyl ether / 2 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In diethyl ether; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jm00058a004

Reference yield:

: 26845-47-6
methyl 1,4-dioxaspiro[4.5]decane-8-carboxylate

: 124499-34-9
1,4-dioxaspiro<4.5>decane-8-ethanamine

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / LAH / diethyl ether / 5 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 2 h / 0 °C

3: dimethylsulfoxide / 3 h / Heating

4: LAH / diethyl ether / 2 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In diethyl ether; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jm00058a004