Tert-butyl [4-(2-amino-ethyl)-phenoxy]-acetate

Base Information

Chemical Name:Tert-butyl [4-(2-amino-ethyl)-phenoxy]-acetate
CAS No.:124499-19-0
Molecular Formula:C14H21 N O3
Molecular Weight:251.32
Hs Code.:2922509090
DSSTox Substance ID:DTXSID20563905
Mol file:124499-19-0.mol

Synonyms:124499-19-0;TERT-BUTYL [4-(2-AMINO-ETHYL)-PHENOXY]-ACETATE;TERT-BUTYL 2-(4-(2-AMINOETHYL)PHENOXY)ACETATE;tert-butyl 2-[4-(2-aminoethyl)phenoxy]acetate;2-[4-(2-aminoethyl)phenoxy]acetic acid tert-butyl ester;tert-butyl2-(4-(2-aminoethyl)phenoxy)acetate;Acetic acid, 2-[4-(2-aminoethyl)phenoxy]-, 1,1-dimethylethyl ester;SCHEMBL9325892;AMY4890;DTXSID20563905;MFCD04114527;AKOS024260391;AB18513;Tert-Butyl[4-(2-aminoethyl)phenoxy]acetate;CS-0272774;tert-Butyl [4-(2-aminoethyl)phenoxy]acetate;tert-Butyl[4-(2-amino-ethyl)-phenoxy]-acetate;A805239;EN300-26432250;tert-butyl 2-[4-(2-azanylethyl)phenoxy]ethanoate;tert-Butyl [4-(2-amino-ethyl)-phenoxy]-acetate, AldrichCPR

Suppliers and Price of Tert-butyl [4-(2-amino-ethyl)-phenoxy]-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl[4-(2-Amino-ethyl)-phenoxy]-acetate
10mg
$ 45.00

J&W Pharmlab
tert-Butyl[4-(2-amino-ethyl)-phenoxy]-acetate 96%
500mg
$ 449.00

J&W Pharmlab
tert-Butyl[4-(2-amino-ethyl)-phenoxy]-acetate 96%
100mg
$ 188.00

American Custom Chemicals Corporation
TERT-BUTYL[4-(2-AMINO-ETHYL)-PHENOXY]-ACETATE 98.00%
5G
$ 1905.75

American Custom Chemicals Corporation
TERT-BUTYL[4-(2-AMINO-ETHYL)-PHENOXY]-ACETATE 98.00%
500MG
$ 721.88

Total 11 raw suppliers

Chemical Property of Tert-butyl [4-(2-amino-ethyl)-phenoxy]-acetate

Chemical Property:

Boiling Point:354.0±22.0 °C(Predicted)
PKA:9.94±0.10(Predicted)
PSA：61.55000
Density:1.064±0.06 g/cm3(Predicted)
LogP:2.60860
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:251.15214353
Heavy Atom Count:18
Complexity:252

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl[4-(2-Amino-ethyl)-phenoxy]-acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)COC1=CC=C(C=C1)CCN

Technology Process of Tert-butyl [4-(2-amino-ethyl)-phenoxy]-acetate

There total 3 articles about Tert-butyl [4-(2-amino-ethyl)-phenoxy]-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124499-21-4
p-(t-butoxycarbonylmethoxy)-phenylacetonitrile

: 124499-19-0
tert-butyl 4-(2-aminoethyl)phenoxyacetate

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; methanol; for 0.166667h; Yield given;
DOI:10.1021/jm00169a015

Reference yield:

: 14191-95-8
4-cyanomethylphenol

: 124499-19-0
tert-butyl 4-(2-aminoethyl)phenoxyacetate

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 16 h / 40 °C

2: aq. CoCl₂, NaBH₄ / tetrahydrofuran; methanol / 0.17 h

With sodium tetrahydroborate; potassium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00169a015

Reference yield:

: 5292-43-3
bromoacetic acid tert-butyl ester

: 124499-19-0
tert-butyl 4-(2-aminoethyl)phenoxyacetate

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 16 h / 40 °C

2: aq. CoCl₂, NaBH₄ / tetrahydrofuran; methanol / 0.17 h

With sodium tetrahydroborate; potassium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00169a015