Cyclopenta[b]pyrrole-2-carboxylic acid, 1,4,5,6-tetrahydro-3-methyl-, methyl ester (9CI)

Base Information

• Chemical Name: Cyclopenta[b]pyrrole-2-carboxylic acid, 1,4,5,6-tetrahydro-3-methyl-, methyl ester (9CI)
• CAS No.: 145696-35-1
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.219
• Mol file: 145696-35-1.mol

Synonyms:Cyclopenta[b]pyrrole-2-carboxylic acid, 1,4,5,6-tetrahydro-3-methyl-, methyl ester (9CI)

Chemical Property of Cyclopenta[b]pyrrole-2-carboxylic acid, 1,4,5,6-tetrahydro-3-methyl-, methyl ester (9CI)

Chemical Property:

• Boiling Point: 337.8±42.0 °C(Predicted)
• PKA: 16.40±0.20(Predicted)
• PSA: 0.00000
• Density: 1.186±0.06 g/cm3(Predicted)
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopenta[b]pyrrole-2-carboxylic acid, 1,4,5,6-tetrahydro-3-methyl-, methyl ester (9CI)

There total 1 articles about Cyclopenta[b]pyrrole-2-carboxylic acid, 1,4,5,6-tetrahydro-3-methyl-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

methyl (Z)-2-(hydroxyimino)-3-oxobutanoate (86459-32-7) + cyclopentanone (120-92-3) → methyl 3-methylcyclopentapyrrole-2-carboxylate (145696-35-1)

Guidance literature:

With sodium proprionate; zinc; In propionic acid; at 120 ℃; for 1h;

upstream raw materials:

methyl (Z)-2-(hydroxyimino)-3-oxobutanoate

cyclopentanone

Refernces