2-But-3-ynyl-oxirane

Base Information

• Chemical Name: 2-But-3-ynyl-oxirane
• CAS No.: 125455-85-8
• Molecular Formula: C₆H₈O
• Molecular Weight: 96.1289
• Hs Code.: 2910900090
• Mol file: 125455-85-8.mol

Synonyms:Oxirane,3-butynyl- (9CI); Oxirane, 3-butynyl-, (?à)-

Chemical Property of 2-But-3-ynyl-oxirane

Chemical Property:

• Vapor Pressure: 24.9mmHg at 25°C
• Refractive Index: 1.464
• Boiling Point: 113.2°Cat760mmHg
• Flash Point: 11.5°C
• PSA: 12.53000
• Density: 0.974g/cm³
• LogP: 0.79860

Purity/Quality:

98%min ^*data from raw suppliers

2-But-3-ynyl-oxirane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-But-3-ynyl-oxirane

There total 1 articles about 2-But-3-ynyl-oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

6-Chloro-5-hydroxy-1-hexyne (125455-84-7) → 5,6-Epoxy-1-hexyne (125455-85-8)

Guidance literature:

With potassium hydroxide; In diethyl ether; at 0 ℃;

DOI:10.1007/BF00957166

Reference yield:

5,6-Epoxy-1-hexyne (125455-85-8) → (+/-)-muscarine iodide (2209-02-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 50 percent / methanol / 3 h / 0 °C

2: NaNH₂ / Heating

3: potassium tert-butylate / 0.08 h / Heating

4: 1.) tetrapropyldiborane, 2.) NaOH, H₂O₂ / 1.) 1 h, 0 deg C, THF

5: diethyl ether / 1 h

With sodium hydroxide; tetra-n-propyl-diborane; potassium tert-butylate; dihydrogen peroxide; sodium amide; In methanol; diethyl ether;

DOI:10.1007/BF00957166

Reference yield:

5,6-Epoxy-1-hexyne (125455-85-8) → 5-Dimethylaminomethyl-2-methyl-4,5-dihydrofuran (125455-83-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 50 percent / methanol / 3 h / 0 °C

2: NaNH₂ / Heating

3: potassium tert-butylate / 0.08 h / Heating

With potassium tert-butylate; sodium amide; In methanol;

DOI:10.1007/BF00957166

upstream raw materials:

6-Chloro-5-hydroxy-1-hexyne

Downstream raw materials:

5-Dimethylaminomethyl-2-methyl-4,5-dihydrofuran

(+/-)-muscarine iodide

Refernces