(6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOL-5-YL)METHANOL

Base Information

• Chemical Name: (6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOL-5-YL)METHANOL
• CAS No.: 76919-41-0
• Molecular Formula: C12H10 N2 O S
• Molecular Weight: 230.29
• Hs Code.: 2934100090
• Mol file: 76919-41-0.mol

Synonyms:NSC332689

Chemical Property of (6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOL-5-YL)METHANOL

Chemical Property:

• Melting Point: 198-200°
• PSA: 65.77000
• Density: 1.37g/cm³
• LogP: 2.55510

Purity/Quality:

97% ^*data from raw suppliers

(6-Phenylimidazo[2,1-b][1,3]thiazol-5-yl)methanol >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOL-5-YL)METHANOL

There total 1 articles about (6-PHENYLIMIDAZO[2,1-B][1,3]THIAZOL-5-YL)METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde (74630-73-2) → 5-idrossimetil-6-fenilimidazo<2,1-b>tiazolo (76919-41-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; 1.) 3 h 15 min, r.t; 2.) 1 h, reflux;

Reference yield:

2,3-dimethoxy-5-methylbenzene-1,4-diol (3066-90-8) + 5-idrossimetil-6-fenilimidazo<2,1-b>tiazolo (76919-41-0) → 2,3-dimethoxy-5-methyl-6-(6-phenyl-imidazo[2,1-b]thiazol-5-ylmethyl)-benzene-1,4-diol

Guidance literature:

With boron trifluoride diethyl etherate; In 1,4-dioxane; at 20 ℃; for 10h;

DOI:10.1016/j.bmc.2004.08.012

Reference yield:

5-idrossimetil-6-fenilimidazo<2,1-b>tiazolo (76919-41-0) → 5-chloromethyl-6-phenyl-imidazo[2,1-b]thiazole

Guidance literature:

With phosphorus pentachloride; In toluene; at 20 ℃; for 5h;

upstream raw materials:

6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde

Downstream raw materials:

(2-Chloro-ethyl)-carbamic acid 6-phenyl-imidazo[2,1-b]thiazol-5-ylmethyl ester

Acetic acid 6-phenyl-imidazo[2,1-b]thiazol-5-ylmethyl ester

Ethyl-carbamic acid 6-phenyl-imidazo[2,1-b]thiazol-5-ylmethyl ester

5-cyanomethyl-6-phenylimidazo<2,1-b>thiazole