Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)- (9CI)

Base Information

• Chemical Name: Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)- (9CI)
• CAS No.: 126720-47-6
• Molecular Formula: C9H8 O2
• Molecular Weight: 148.161
• Mol file: 126720-47-6.mol

Synonyms:Oxiranecarboxaldehyde,3-phenyl-, (2R,3S)- (9CI); Oxiranecarboxaldehyde, 3-phenyl-, (2R-trans)-;(2R,3S)-3-Phenyloxirane-2-carboxaldehyde

Chemical Property of Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)- (9CI)

Chemical Property:

• PSA: 29.60000
• LogP: 1.32540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)- (9CI)

There total 57 articles about Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(2S,3S)-2,3-epoxy-3-phenyl-1-propanol (104196-23-8) → (2R,3S)-3-phenyloxirane-2-carbaldehyde (126720-47-6)

Guidance literature:

With sulfur trioxide pyridine complex; triethylamine; In dichloromethane; dimethyl sulfoxide; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c8ob00165k

Reference yield: 80.0%

(2E)-3-phenyl-2-propen-1-ol (4407-36-7) → (2S,3S)-3-phenyloxirane-2-carbaldehyde (5693-99-2,71403-94-6,99773-54-3,119951-98-3,121651-02-3,126720-47-6)

Guidance literature:

DOI:10.1016/S0040-4039(00)80680-2

Reference yield: 80.0%

(E)-3-phenylpropenal (14371-10-9) → (±)-3-phenyloxirane-2-carbaldehyde (5693-99-2,71403-94-6,99773-54-3,119951-98-3,121651-02-3,126720-47-6)

Guidance literature:

With tert.-butylhydroperoxide; tetrabutyl ammonium fluoride; In dimethyl sulfoxide; toluene; at 17 ℃; for 1.5h;

DOI:10.1246/cl.1987.285

upstream raw materials:

(E)-3-phenylpropenal

trans-2,3-epoxy-3-phenylpropan-1-ol

2,3-epoxy-3-phenyl-1-propanol

(2E)-3-phenyl-2-propen-1-ol

Downstream raw materials:

2-Phenyl-3-<4-phenyl-1(Z),3(E)-butadienyl>oxiran

2-Phenyl-3-<4-phenyl-1(E),3(E)-butadienyl>oxiran

5-(3-Phenyl-2-oxiranyl)-2(E),4(Z)-pentadiensaeure-methylester

5-(3-Phenyl-2-oxiranyl)-2(E),4(E)-pentadiensaeure-methylester