Tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate
CAS No.:135716-09-5
Molecular Formula:C14H25NO4
Molecular Weight:271.357
Hs Code.:2933399090
European Community (EC) Number:690-045-8
DSSTox Substance ID:DTXSID70433881
Wikidata:Q72503086
Mol file:135716-09-5.mol

Synonyms:135716-09-5;TERT-BUTYL 4-(2-ETHOXY-2-OXOETHYL)PIPERIDINE-1-CARBOXYLATE;Ethyl N-BOC-piperidine-4-acetate;ETHYL N-BOC-4-PIPERIDINEACETATE;N-Boc-4-ethyl piperidinecarboxylate;MFCD08275143;4-PIPERIDINEACETIC ACID, 1-[(1,1-DIMETHYLETHOXY)CARBONYL]-, ETHYL ESTER;4-ethoxycarbonylmethyl-piperidine-1-carboxylic acid tert-butyl ester;1-BOC-4-(2-ETHOXY-2-OXOETHYL)PIPERIDINE;Phenylvinylsulfide;1-Boc-4-Piperidine acetate ethyl ester;1-Boc-4-piperidineacetic acid ethyl ester;SCHEMBL785988;Ethyl 1-Boc-4-piperidineacetate;DTXSID70433881;PQEXLIRUMIRSAL-UHFFFAOYSA-N;BCP26963;CS-M1537;AKOS015907781;PB38948;SB20079;DS-14432;SY016960;Ethyl N-t-Butoxycarbonyl-4-piperidylacetate;AM20080264;FT-0648865;EN300-200408;ethyl N-tert-butoxycarbonyl-4-piperidineacetate;ethyl(1-t-butoxycarbonylpiperidin-4-yl)acetate;ethyl (1-t-butoxycarbonylpiperidin-4-yl)acetate;ethyl 2-(1-tert-butoxycarbonyl-piperidin-4-yl)acetate;Z902498678;1-(tert-butoxycarbonyl)-4-piperidineacetic acid ethyl ester;ethyl 1-[(1,1-dimethylethoxy)carbonyl]-4-piperidineacetate;2-(l -t-Butoxycarbonyl-4-piperidyl)ethanoic Acid Ethyl Ester;4-Ethoxycarbonylmethylpiperidine-1-carboxylic acid tert-butyl ester;t-butyl 4-(2-ethoxy-2-oxoethyl)-tetrahydropyridine-1(2H)-carboxylate;t-butyl 4-(2-ethoxy-2-oxoethyl)tetrahydro-pyridine-1(2H)-carboxylate;t-butyl 4-(2-ethoxy-2-oxoethyl)tetrahydropyridine-1(2H)-carboxylate;tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate, AldrichCPR

Suppliers and Price of Tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
EthylN-Boc-piperidine-4-acetate
1g
$ 75.00

TRC
EthylN-Boc-piperidine-4-acetate
250mg
$ 55.00

SynQuest Laboratories
Ethyl 1-Boc-4-piperidine acetate
5 g
$ 75.00

SynQuest Laboratories
Ethyl 1-Boc-4-piperidine acetate
1 g
$ 45.00

SynQuest Laboratories
Ethyl 1-Boc-4-piperidine acetate
25 g
$ 265.00

Sigma-Aldrich
tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate Aldrich
1g
$ 135.00

Matrix Scientific
tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate
500mg
$ 119.00

ChemScene
4-Piperidineaceticacid,1-[(1,1-dimethylethoxy)carbonyl]-,ethylester ≥98.0%
25g
$ 85.00

ChemScene
4-Piperidineaceticacid,1-[(1,1-dimethylethoxy)carbonyl]-,ethylester ≥98.0%
100g
$ 208.00

Chemenu
tert-Butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate 97%
100g
$ 222.00

Total 38 raw suppliers

Chemical Property of Tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Chemical Property:

Boiling Point:339.2±15.0 °C(Predicted)
PKA:-1?+-.0.40(Predicted)
PSA：55.84000
Density:1.048±0.06 g/cm3(Predicted)
LogP:2.52460
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:271.17835828
Heavy Atom Count:19
Complexity:314

Purity/Quality:

98% ^*data from raw suppliers

EthylN-Boc-piperidine-4-acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1CCN(CC1)C(=O)OC(C)(C)C

Technology Process of Tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

There total 15 articles about Tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate: 135716-08-4
tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

: 135716-09-5
tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Guidance literature:: With hydrogen; 10% palladium on active carbon; In ethyl acetate; for 3h; under 3750.3 Torr;
DOI:10.3987/com-00-8965

Reference yield: 96.5%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 135716-09-5
tert-butyl 4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With potassium tert-butylate; In tetrahydrofuran; at 0 - 5 ℃; for 1h;

N-tert-butyloxycarbonylpiperidin-4-one; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 24h; under 760.051 Torr;
DOI:10.1016/j.ejmech.2016.07.038