Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, cis- (9CI)

Base Information

• Chemical Name: Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, cis- (9CI)
• CAS No.: 130023-71-1
• Molecular Formula: C₆H₁₂N₂O₂
• Molecular Weight: 144.173
• Mol file: 130023-71-1.mol

Synonyms:Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, cis- (9CI)

Chemical Property of Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, cis- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, cis- (9CI)

There total 5 articles about Cyclopentanecarboxylic acid, 2-hydroxy-, hydrazide, cis- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethyl trans-2-hydroxy-1-cyclopentane carboxylate (1883-91-6,2315-21-1,54972-10-0,61586-79-6,63599-14-4,63599-15-5,110611-67-1,110611-68-2,122331-03-7) → (+/-)-trans-2-hydroxy-cyclopentane-carboxylic acid-(1)-hydrazide (130023-71-1,130023-72-2,216879-03-7)

Guidance literature:

With hydrazine hydrate; In ethanol; for 1h; Heating;

Reference yield: 90.0%

ethyl cis-(±)-2-hydroxycyclopentane-1-carboxylate (1883-91-6,2315-21-1,54972-10-0,61586-79-6,63599-14-4,63599-15-5,110611-67-1,110611-68-2,122331-03-7) → (+/-)-cis-2-hydroxy-cyclopentane-carboxylic acid-(1)-hydrazide (130023-71-1,130023-72-2,216879-03-7)

Guidance literature:

With hydrazine hydrate; In ethanol; for 1h; Heating;

Reference yield:

(+/-)-trans-2-(3.5-dinitro-benzoyloxy)-cyclopentane-carboxylic acid-(1)-ethyl ester (63578-04-1) → (+/-)-trans-2-hydroxy-cyclopentane-carboxylic acid-(1)-hydrazide (130023-71-1,130023-72-2,216879-03-7)

Guidance literature:

Multi-step reaction with 2 steps

1: /BRN= 3196781/

2: ethanol; hydrazine hydrate

With ethanol; hydrazine hydrate;

DOI:10.1021/ja01131a054

upstream raw materials:

ethyl cis-(±)-2-hydroxycyclopentane-1-carboxylate

2-ethoxycarbonyl-1-cyclopentanone

(+/-)-cis-2-(3,5-dinitro-benzoyloxy)-cyclopentane-carboxylic acid-⁽¹⁾-ethyl ester

ethyl trans-2-hydroxy-1-cyclopentane carboxylate

Downstream raw materials:

C₁₃H₁₇N₃O₃

C₁₃H₁₇N₃O₂S

(1S,2R)-2-(5-Phenylamino-[1,3,4]oxadiazol-2-yl)-cyclopentanol

(1S,2R)-2-(5-Phenylamino-[1,3,4]thiadiazol-2-yl)-cyclopentanol