6-Hydroxynaphthalene-1-carbonitrile

Base Information

Chemical Name:6-Hydroxynaphthalene-1-carbonitrile
CAS No.:130200-57-6
Molecular Formula:C11H7 N O
Molecular Weight:169.183
Hs Code.:2926909090
European Community (EC) Number:855-415-7
DSSTox Substance ID:DTXSID70695402
Nikkaji Number:J633.568C
Wikidata:Q82624570
Mol file:130200-57-6.mol

Synonyms:6-Hydroxynaphthalene-1-carbonitrile;130200-57-6;6-Hydroxy-1-naphthonitrile;5-Cyano-2-naphthol;6-HYDROXY-NAPHTHALENE-1-CARBONITRILE;1-Naphthalenecarbonitrile, 6-hydroxy-;1-Cyano-6-naphthol;SCHEMBL112288;DTXSID70695402;BSQTUYCOTSTNLF-UHFFFAOYSA-N;6-Hydroxy-1-naphthalenecarbonitrile;CS-0373341;FT-0750501;EN300-8110949;Z1255403780

Suppliers and Price of 6-Hydroxynaphthalene-1-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
6-Hydroxy-naphthalene-1-carbonitrile 97
5g
$ 1833.00

Alichem
1-Cyano-6-naphthol
1g
$ 1718.70

Alichem
1-Cyano-6-naphthol
500mg
$ 989.80

Total 30 raw suppliers

Chemical Property of 6-Hydroxynaphthalene-1-carbonitrile

Chemical Property:

PSA：44.02000
LogP:2.41708
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:169.052763847
Heavy Atom Count:13
Complexity:230

Purity/Quality:

99% ^*data from raw suppliers

6-Hydroxy-naphthalene-1-carbonitrile 97 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2)O)C(=C1)C#N

Technology Process of 6-Hydroxynaphthalene-1-carbonitrile

There total 4 articles about 6-Hydroxynaphthalene-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 77029-01-7
6-methoxy-[1]naphthonitrile

: 130200-57-6
6-hydroxynaphthalene-1-carbonitrile

Guidance literature:: With sodium cyanide; In dimethyl sulfoxide; at 160 - 170 ℃; for 12h; Yield given;
DOI:10.1021/ja00102a028

Reference yield:

: 6398-50-1
6-methoxy-3,4-dihydronaphthalene-1-carbonitrile

: 130200-57-6
6-hydroxynaphthalene-1-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: sulfur, 5percent Pd/C / 2 h / 190 - 200 °C

2: NaCN / dimethylsulfoxide / 12 h / 160 - 170 °C

With palladium on activated charcoal; sodium cyanide; sulfur; In dimethyl sulfoxide;
DOI:10.1021/ja00102a028

Reference yield:

: 1078-19-9
6-methoxy-3,4-dihydro-1(2H)-naphthalenone

: 130200-57-6
6-hydroxynaphthalene-1-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) BF₃*Et₂O, 2.) pyridine, POCl₃ / 1.) a) 60 deg C, 2 h, b) 90 deg C, 2 h, 2.) heating

2: sulfur, 5percent Pd/C / 2 h / 190 - 200 °C

3: NaCN / dimethylsulfoxide / 12 h / 160 - 170 °C

With pyridine; palladium on activated charcoal; boron trifluoride diethyl etherate; sodium cyanide; sulfur; trichlorophosphate; In dimethyl sulfoxide;
DOI:10.1021/ja00102a028