cis-2-Chloro-2-fluorocyclopropanamine hydrochloride

Base Information

• Chemical Name: cis-2-Chloro-2-fluorocyclopropanamine hydrochloride
• CAS No.: 130340-10-2
• Molecular Formula: C₃H₅ClFN*ClH
• Molecular Weight: 145.992
• Hs Code.: 2921300090
• DSSTox Substance ID: DTXSID70697840
• Mol file: 130340-10-2.mol

Synonyms:CIS-2-CHLORO-2-FLUOROCYCLOPROPANAMINE HYDROCHLORIDE;DTXSID70697840;130340-17-9;AKOS006359742;2-CHLORO-2-FLUOROCYCLOPROPAN-1-AMINE HYDROCHLORIDE;2-Chloro-2-fluorocyclopropan-1-amine--hydrogen chloride (1/1)

Chemical Property of cis-2-Chloro-2-fluorocyclopropanamine hydrochloride

Chemical Property:

• PSA: 26.02000
• LogP: 2.12430
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 144.9861327
• Heavy Atom Count: 7
• Complexity: 77.2

Purity/Quality:

TRANS-2-CHLORO-2-FLUOROCYCLOPROPANEAMINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:
• Hazard Codes: R36/37/38:
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(C1(F)Cl)N.Cl

Technology Process of cis-2-Chloro-2-fluorocyclopropanamine hydrochloride

There total 1 articles about cis-2-Chloro-2-fluorocyclopropanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Chloro-1-fluoro-2-isocyanato-cyclopropane (130340-09-9) → 2-Chloro-2-fluoro-cyclopropylamine; hydrochloride (130340-10-2,130340-17-9)

Guidance literature:

With hydrogenchloride; In toluene; at 60 ℃; Yield given;

DOI:10.1016/S0022-1139(00)80369-3

upstream raw materials:

1-Chloro-1-fluoro-2-isocyanato-cyclopropane