2-Amino-5-cyano-6-ethoxypyridine-3-carboxylic acid

Base Information

Chemical Name:2-Amino-5-cyano-6-ethoxypyridine-3-carboxylic acid
CAS No.:130484-87-6
Molecular Formula:C₉H₉N₃O₃
Molecular Weight:207.189
Hs Code.:
DSSTox Substance ID:DTXSID80562994
Nikkaji Number:J341.153B
Wikidata:Q82447337
Mol file:130484-87-6.mol

Synonyms:130484-87-6;2-Amino-5-cyano-6-ethoxypyridine-3-carboxylic acid;3-Pyridinecarboxylicacid,2-amino-5-cyano-6-ethoxy-(9CI);DTXSID80562994

Suppliers and Price of 2-Amino-5-cyano-6-ethoxypyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Amino-5-cyano-6-ethoxypyridine-3-carboxylic acid

Chemical Property:

PSA：109.23000
LogP:1.21358
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:207.06439116
Heavy Atom Count:15
Complexity:286

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=NC(=C(C=C1C#N)C(=O)O)N

Technology Process of 2-Amino-5-cyano-6-ethoxypyridine-3-carboxylic acid

There total 2 articles about 2-Amino-5-cyano-6-ethoxypyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 130503-89-8
Ethyl 5-amino-2,4-dicyano-5-ethoxy-2,4-pentadienoate

: 130484-87-6
2-Amino-5-cyano-6-ethoxy-nicotinic acid

: 130484-75-2
Ethyl 2-amino-5-cyano-6-ethoxynicotinate

Guidance literature:: With sodium ethanolate; for 1h; Ambient temperature;

Reference yield:

: 42003-88-3
ethyl 2-cyanoacetimidate

: 130484-87-6
2-Amino-5-cyano-6-ethoxy-nicotinic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / ethanol / 1 h

2: 8 percent / sodium ethoxide / 1 h / Ambient temperature

With sodium ethanolate; In ethanol;