(E)-3-(4-FLUORO-PHENYL)-ACRYLIC ACID BUTYL ESTER

Base Information

• Chemical Name: (E)-3-(4-FLUORO-PHENYL)-ACRYLIC ACID BUTYL ESTER
• CAS No.: 131061-12-6
• Molecular Formula: C13H15FO2
• Molecular Weight: 222.259
• Hs Code.: 2916399090
• Mol file: 131061-12-6.mol

Synonyms:(E)-3-(4-FLUORO-PHENYL)-ACRYLIC ACID BUTYL ESTER

Chemical Property of (E)-3-(4-FLUORO-PHENYL)-ACRYLIC ACID BUTYL ESTER

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Melting Point: 209-210 °C
• Refractive Index: 1.524
• Boiling Point: 302.555°C at 760 mmHg
• Flash Point: 132.437°C
• PSA: 26.30000
• Density: 1.089g/cm³
• LogP: 3.18220

Purity/Quality:

(E)-3-(4-FLUORO-PHENYL)-ACRYLIC ACID BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-3-(4-FLUORO-PHENYL)-ACRYLIC ACID BUTYL ESTER

There total 9 articles about (E)-3-(4-FLUORO-PHENYL)-ACRYLIC ACID BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 4-fluoro-1-iodobenzene (352-34-1) → (E)-n-butyl 3-(4-fluorophenyl)acrylate (131061-12-6)

Guidance literature:

With tributyl-amine; chloro-[2-(9-phenyl-1,10-phenanthrolin-2-yl)phenyl]palladium; In 1-methyl-pyrrolidin-2-one; at 140 ℃; for 15h; Inert atmosphere;

DOI:10.1002/adsc.201800099

Reference yield: 90.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 1-Bromo-4-fluorobenzene (460-00-4) → (E)-n-butyl 3-(4-fluorophenyl)acrylate (131061-12-6)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In water; at 98 ℃; for 3h; Catalytic behavior; Schlenk technique;

DOI:10.1039/c7gc02869e

Reference yield: 88.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 4-fluoroboronic acid (1765-93-1) → (E)-n-butyl 3-(4-fluorophenyl)acrylate (131061-12-6)

Guidance literature:

With polystyrene-immobilised phenanthroline palladium catalyst; air; In N,N-dimethyl-formamide; at 100 ℃; for 28h;

DOI:10.3184/174751912X13466942543952

upstream raw materials:

acrylic acid n-butyl ester

4-Fluorobenzenesulfonyl chloride

1-Bromo-4-fluorobenzene

4-fluoro-1-iodobenzene