Pyrrolidine, 1-(2-fluoro-3-methyl-1-oxopentyl)-2,5-dimethyl-, [2R-[1(2R,3S),2alpha,5beta]]- (9CI)

Base Information

Chemical Name:Pyrrolidine, 1-(2-fluoro-3-methyl-1-oxopentyl)-2,5-dimethyl-, [2R-[1(2R*,3S*),2alpha,5beta]]- (9CI)
CAS No.:136634-13-4
Molecular Formula:C12H22FNO
Molecular Weight:215.31
Hs Code.:
Mol file:136634-13-4.mol

Synonyms:Pyrrolidine, 1-(2-fluoro-3-methyl-1-oxopentyl)-2,5-dimethyl-, [2R-[1(2R*,3S*),2alpha,5beta]]- (9CI)

Suppliers and Price of Pyrrolidine, 1-(2-fluoro-3-methyl-1-oxopentyl)-2,5-dimethyl-, [2R-[1(2R*,3S*),2alpha,5beta]]- (9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pyrrolidine, 1-(2-fluoro-3-methyl-1-oxopentyl)-2,5-dimethyl-, [2R-[1(2R*,3S*),2alpha,5beta]]- (9CI)

Chemical Property:

PSA：20.31000
LogP:2.70790

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Pyrrolidine, 1-(2-fluoro-3-methyl-1-oxopentyl)-2,5-dimethyl-, [2R-[1(2R*,3S*),2alpha,5beta]]- (9CI)

There total 4 articles about Pyrrolidine, 1-(2-fluoro-3-methyl-1-oxopentyl)-2,5-dimethyl-, [2R-[1(2R*,3S*),2alpha,5beta]]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 136634-11-2
N-fluoroacetyl-trans-(2R,5R)-2,5-dimethylpyrrolidine

: 136634-13-4
(2R,3S)-1-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-2-fluoro-3-methyl-pentan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 0.5 h / Ambient temperature

2: CH₂Cl₂ / 24 h / Ambient temperature

3: H₂ / Pd-C

With hydrogen; palladium on activated charcoal; In dichloromethane;
DOI:10.1016/S0040-4039(00)92145-2

Reference yield:

: Trifluoro-methanesulfonate(2R,5R)-1-(2-fluoro-1-methoxy-ethylidene)-2,5-dimethyl-pyrrolidinium;

: 136634-13-4
(2R,3S)-1-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-2-fluoro-3-methyl-pentan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 24 h / Ambient temperature

2: H₂ / Pd-C

With hydrogen; palladium on activated charcoal; In dichloromethane;
DOI:10.1016/S0040-4039(00)92145-2