Cyclopenta[b]pyrrol-2(1H)-one, hexahydro-, (3aR-cis)- (9CI)

Base Information

Chemical Name:Cyclopenta[b]pyrrol-2(1H)-one, hexahydro-, (3aR-cis)- (9CI)
CAS No.:131348-75-9
Molecular Formula:C7H11NO
Molecular Weight:125.16834
Hs Code.:
Mol file:131348-75-9.mol

Synonyms:Cyclopenta[b]pyrrol-2(1H)-one, hexahydro-, (3aR-cis)- (9CI)

Suppliers and Price of Cyclopenta[b]pyrrol-2(1H)-one, hexahydro-, (3aR-cis)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
(3aR,6aR)-hexahydro-Cyclopenta[b]pyrrol-2(1H)-one 97.00%
25G
$ 12900.00

AccelPharmtech
(3aR,6aR)-hexahydro-Cyclopenta[b]pyrrol-2(1H)-one 97.00%
5G
$ 6840.00

AccelPharmtech
(3aR,6aR)-hexahydro-Cyclopenta[b]pyrrol-2(1H)-one 97.00%
1G
$ 3960.00

Total 5 raw suppliers

Chemical Property of Cyclopenta[b]pyrrol-2(1H)-one, hexahydro-, (3aR-cis)- (9CI)

Chemical Property:

PSA：29.10000
LogP:1.00380

Purity/Quality:

98% ^*data from raw suppliers

(3aR,6aR)-hexahydro-Cyclopenta[b]pyrrol-2(1H)-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Cyclopenta[b]pyrrol-2(1H)-one, hexahydro-, (3aR-cis)- (9CI)

There total 6 articles about Cyclopenta[b]pyrrol-2(1H)-one, hexahydro-, (3aR-cis)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 125355-92-2
((1R,2R)-2-Amino-cyclopentyl)-acetic acid ethyl ester; hydrochloride

: 131348-75-9,214263-63-5
(-)-(R)-hexahydro-cyclopenta[b]pyrrol-2-one

Guidance literature:: With sodium hydroxide; for 2h; Heating; or conc. NH₃;
DOI:10.1002/ardp.19903231109

Reference yield: 53.0%

: 1541989-30-3
(3aR,6aR)-1-(1-phenylvinyl)hexahydrocyclopenta[b]pyrrol-2(1H)-one

: 131348-75-9,214263-63-5
(-)-(R)-hexahydro-cyclopenta[b]pyrrol-2-one

Guidance literature:: With hydrogenchloride; In methanol; water; at 20 ℃; for 1h;

Reference yield:

: 104115-44-8,1460-38-4
(2-oxocyclopent)acetic acid

: 131348-75-9,214263-63-5
(-)-(R)-hexahydro-cyclopenta[b]pyrrol-2-one

Guidance literature:: Multi-step reaction with 5 steps

1: 3 h / 130 °C / Heating

2: boron trifluoride diethyl etherate; triethylsilane / dichloromethane / 20 h / 50 °C

3: p-toluenesulfonyl chloride; pyridine / dichloromethane / 0.92 h / 0 - 20 °C

4: 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 2 h / Reflux

5: hydrogenchloride / methanol; water / 1 h / 20 °C

With pyridine; hydrogenchloride; triethylsilane; boron trifluoride diethyl etherate; 1,8-diazabicyclo[5.4.0]undec-7-ene; p-toluenesulfonyl chloride; In methanol; dichloromethane; water; toluene;