Methyl 6-piperazinonicotinate

Base Information

Chemical Name:Methyl 6-piperazinonicotinate
CAS No.:132144-03-7
Molecular Formula:C11H15N3O2
Molecular Weight:221.26
Hs Code.:2933599090
DSSTox Substance ID:DTXSID40566599
Wikidata:Q82452282
Mol file:132144-03-7.mol

Synonyms:132144-03-7;methyl 6-piperazinonicotinate;Methyl 6-(piperazin-1-yl)nicotinate;methyl 6-(piperazin-1-yl)pyridine-3-carboxylate;methyl 6-piperazin-1-ylpyridine-3-carboxylate;3-Pyridinecarboxylic acid, 6-(1-piperazinyl)-, methyl ester;6-(1-Piperazinyl)-3-pyridinecarboxylic acid methyl ester;2-(1-piperazinyl)-5-pyridinecarboxylic acid methyl ester;SCHEMBL532001;DTXSID40566599;HMFYTTJLIFNUCP-UHFFFAOYSA-N;methyl 6-(1-piperazinyl)nicotinate;MFCD00894966;AKOS005071994;CC-0811;CS-0444547;EN300-1071781;J-522517

Suppliers and Price of Methyl 6-piperazinonicotinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Methyl 6-piperazinonicotinate
1 g
$ 332.00

Matrix Scientific
Methyl 6-piperazinonicotinate >95%
500mg
$ 390.00

Matrix Scientific
Methyl 6-piperazinonicotinate >95%
1g
$ 600.00

Crysdot
Methyl6-(piperazin-1-yl)nicotinate 95+%
1g
$ 454.00

American Custom Chemicals Corporation
6-(1-PIPERAZINYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 496.49

AK Scientific
Methyl6-piperazinonicotinate
1g
$ 860.00

aablocks
Methyl6-piperazinonicotinate >95%
1g
$ 405.00

aablocks
Methyl6-piperazinonicotinate >95%
500mg
$ 325.00

aablocks
Methyl6-piperazinonicotinate >95%
10mg
$ 187.00

aablocks
Methyl6-piperazinonicotinate >95%
1mg
$ 152.00

Total 9 raw suppliers

Chemical Property of Methyl 6-piperazinonicotinate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:165～167℃
Refractive Index:1.545
Boiling Point:395.033°C at 760 mmHg
PKA:8.52±0.10(Predicted)
Flash Point:192.709°C
PSA：54.46000
Density:1.172g/cm³
LogP:0.67160
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:221.116426730
Heavy Atom Count:16
Complexity:241

Purity/Quality:

99%, ^*data from raw suppliers

Methyl 6-piperazinonicotinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CN=C(C=C1)N2CCNCC2

Technology Process of Methyl 6-piperazinonicotinate

There total 2 articles about Methyl 6-piperazinonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 110-85-0
piperazine

: 73781-91-6
6-Chloronicotinic acid methyl ester

: 132144-03-7
2-(1-piperazinyl)-5-pyridinecarboxylic acid methyl ester

Guidance literature:: In methanol; at 60 ℃; for 6h;

Reference yield:

: 110-85-0
piperazine

: 26218-78-0
methyl 6-bromonicotinate

: 132144-03-7
2-(1-piperazinyl)-5-pyridinecarboxylic acid methyl ester

Guidance literature:: In dichloromethane; acetonitrile;

Reference yield:

: 287114-20-9
1,5-dimethyl-2-phenylindole-3-carboxylic acid

: 132144-03-7
2-(1-piperazinyl)-5-pyridinecarboxylic acid methyl ester

: 521985-01-3
6-{4-[(1,5-dimethyl-2-phenyl-1H-indol-3-yl)carbonyl]piperazin-1-yl}nicotinic acid methyl ester

Guidance literature:: 1,5-dimethyl-2-phenylindole-3-carboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In DMF (N,N-dimethyl-formamide); for 0.5h;

2-(1-piperazinyl)-5-pyridinecarboxylic acid methyl ester; In DMF (N,N-dimethyl-formamide); at 20 ℃;