N-Desmethyltramadol

Base Information

Chemical Name:N-Desmethyltramadol
CAS No.:73806-55-0
Molecular Formula:C15H23 N O2
Molecular Weight:249.353
Hs Code.:2906199090
European Community (EC) Number:641-577-4
DSSTox Substance ID:DTXSID50891485
Nikkaji Number:J77.828A
Mol file:73806-55-0.mol

Synonyms:N-demethyltramadol;N-demethyltramadol hydrochloride;N-desmethyltramadol

Suppliers and Price of N-Desmethyltramadol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Desmethyltramadol

Chemical Property:

Vapor Pressure:9.16E-07mmHg at 25°C
Boiling Point:389.5°C at 760 mmHg
PKA:14.46±0.40(Predicted)
Flash Point:189.4°C
PSA：41.49000
Density:1.054g/cm³
LogP:2.68330
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:249.172878976
Heavy Atom Count:18
Complexity:259

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC1CCCCC1(C2=CC(=CC=C2)OC)O

Technology Process of N-Desmethyltramadol

There total 3 articles about N-Desmethyltramadol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1426536-05-1
C₁₈H₂₇NO₄

: 73806-55-0,147762-57-0,75377-45-6
2-methylaminomethyl-1-(3-methoxyphenyl)-cyclohexanol

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 5 - 10 ℃; for 3h;

Reference yield:

: 1426536-04-0
C₁₁H₁₉NO₃

: 73806-55-0,147762-57-0,75377-45-6
2-methylaminomethyl-1-(3-methoxyphenyl)-cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 0.75 h / -78 °C / Inert atmosphere

1.2: 2 h / -78 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 3 h / 5 - 10 °C

With n-butyllithium; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;