R-(-)-Manidipine

Base Information Edit

Chemical Name:R-(-)-Manidipine
CAS No.:133082-19-6
Molecular Formula:C₃₅H₃₈N₄O₆
Molecular Weight:610.71
Hs Code.:
UNII:R803FSR459
DSSTox Substance ID:DTXSID00545486
Wikidata:Q27287944
Mol file:133082-19-6.mol

Synonyms:(+)-manidipine;(+)-manidipine dihydrochloride;(-)-manidipine;(-)-manidipine dihydrochloride;(R)-(-)-manidipine;(R)-(-)-manidipine dihydrochloride;(R)-manidipine;(R)-manidipine dihydrochloride;(S)-(+)-manidipine;(S)-(+)-manidipine dihydrochloride;(S)-manidipine;(S)-manidipine dihydrochloride;2-(4-diphenylmethyl-1-piperazinyl)ethyl methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate;CV 4093;CV-4093;manidipine;manidipine dihydrochloride;manidipine hydrochloride;manidipine, (+-)-isomer

Suppliers and Price of R-(-)-Manidipine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
R-(-)-Manidipine
10mg
$ 475.00

Medical Isotopes, Inc.
R-(-)-Manidipine
5 mg
$ 2440.00

American Custom Chemicals Corporation
R-MANIDIPINE 95.00%
1MG
$ 374.85

American Custom Chemicals Corporation
R-MANIDIPINE 95.00%
10MG
$ 1963.50

A2B
3,5-Pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-[4-(diphenylmethyl)-1-piperazinyl]ethylmethylester,(4R)-(9CI)
5mg
$ 3100.00

A2B
3,5-Pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-[4-(diphenylmethyl)-1-piperazinyl]ethylmethylester,(4R)-(9CI)
1mg
$ 1213.00

Total 8 raw suppliers

Chemical Property of R-(-)-Manidipine Edit

Chemical Property:

Vapor Pressure:1.07E-20mmHg at 25°C
Refractive Index:1.6
Boiling Point:722°C at 760 mmHg
PKA:6.12±0.10(Predicted)
Flash Point:390.4°C
PSA：116.93000
Density:1.232g/cm³
LogP:6.15140
XLogP3:5.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:11
Exact Mass:610.27913494
Heavy Atom Count:45
Complexity:1090

Purity/Quality:

97% ^*data from raw suppliers

R-(-)-Manidipine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC
Isomeric SMILES:CC1=C([C@H](C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC
Uses (R)-Manidipine enantiomer. A dihydropyridine calcium channel blocker. Antihypertensive R-(-)-Manidipine Hydrochloride is the (R) stereoisomer of Manidipine (M164000), a dihydropyridine calcium channel blocker. Antihypertensive.

Technology Process of R-(-)-Manidipine

There total 18 articles about R-(-)-Manidipine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%