cis-4-Amino-1-benzylpiperidin-3-ol

Base Information

Chemical Name:cis-4-Amino-1-benzylpiperidin-3-ol
CAS No.:133341-84-1
Molecular Formula:C₁₂H₁₈N₂O
Molecular Weight:206.288
Hs Code.:2933399090
Mol file:133341-84-1.mol

Synonyms:cis-4-Amino-1-benzylpiperidin-3-ol;cis-4-Amino-1-benzylpiperidin-3-ol 2HCl

Suppliers and Price of cis-4-Amino-1-benzylpiperidin-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3S,4R)-4-AMINO-1-BENZYLPIPERIDIN-3-OL 95.00%
5MG
$ 501.81

Total 2 raw suppliers

Chemical Property of cis-4-Amino-1-benzylpiperidin-3-ol

Chemical Property:

Vapor Pressure:1.05E-05mmHg at 25°C
Refractive Index:1.59
Boiling Point:356.7°Cat760mmHg
Flash Point:169.5°C
PSA：49.49000
Density:1.143g/cm³
LogP:1.21870

Purity/Quality:

99% ^*data from raw suppliers

(3S,4R)-4-AMINO-1-BENZYLPIPERIDIN-3-OL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of cis-4-Amino-1-benzylpiperidin-3-ol

There total 6 articles about cis-4-Amino-1-benzylpiperidin-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 133341-78-3,133341-87-4
1-Benzyl-3-hydroxy-piperidin-4-one O-benzyl-oxime

: 86717-83-1,86717-84-2,104860-47-1,133341-84-1
4-amino-1-benzylpiperidin-3-ol

Guidance literature:: With borane-THF; In tetrahydrofuran; for 16h; 0 deg C to r.t.;
DOI:10.1016/S0040-4039(00)74864-7

Reference yield:

: 4-azido-1-benzylpiperidin-3-ol

: 86717-83-1,86717-84-2,104860-47-1,133341-84-1
4-amino-1-benzylpiperidin-3-ol

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; water;

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 86717-83-1,86717-84-2,104860-47-1,133341-84-1
4-amino-1-benzylpiperidin-3-ol

Guidance literature:: Multi-step reaction with 3 steps

1: KOH, iodobenzenediacetate / 16 h / 0 deg C to r.t.

2: 1) 3N aq.HCl, 2) pyridine / 1) EtOH, r.t., 2 h, 2) 16 h

3: 74 percent / BH₃*THF / tetrahydrofuran / 16 h / 0 deg C to r.t.

With pyridine; hydrogenchloride; potassium hydroxide; borane-THF; [bis(acetoxy)iodo]benzene; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)74864-7