Cyclopropanecarboxylic acid, 1-amino-2-(phosphonomethyl)-, (1R,2S)-rel-

Base Information

Chemical Name:Cyclopropanecarboxylic acid, 1-amino-2-(phosphonomethyl)-, (1R,2S)-rel-
CAS No.:133753-34-1
Molecular Formula:C5H10NO5P
Molecular Weight:195.11
Hs Code.:
Mol file:133753-34-1.mol

Synonyms:Cyclopropanecarboxylic acid, 1-amino-2-(phosphonomethyl)-, (1R,2S)-rel-

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Chemical Property of Cyclopropanecarboxylic acid, 1-amino-2-(phosphonomethyl)-, (1R,2S)-rel-

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Technology Process of Cyclopropanecarboxylic acid, 1-amino-2-(phosphonomethyl)-, (1R,2S)-rel-

There total 4 articles about Cyclopropanecarboxylic acid, 1-amino-2-(phosphonomethyl)-, (1R,2S)-rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 133753-40-9,133753-41-0
(Z)-(2RS,3SR)-methyl 2--2,3-methano-4-(diethylphosphinyl)butanoate

: 133753-34-1,133753-35-2,139489-49-9,139489-50-2
(Z)-(2RS,3SR)-2-amino-2,3-methano-4-phosphonobutanoic acid

Guidance literature:: With hydrogenchloride; for 18h; Heating;
DOI:10.1021/jm00109a023

Reference yield: 36.3%

: 133753-40-9,133753-41-0
(E)-(2RS,3RS)-methyl 2--2,3-methano-4-(diethylphosphinyl)butanoate

: 133753-34-1,133753-35-2,139489-49-9,139489-50-2
(E)-(2RS,3RS)-2-amino-2,3-methano-4-phosphonobutanoic acid

Guidance literature:: With hydrogenchloride; for 9h; Heating;
DOI:10.1021/jm00109a023

Reference yield:

: 133753-38-5,133753-39-6
(E)-(3RS,4SR)-methyl 3--4-<(diethoxyphosphinyl)methyl>pyrazoline-3-carboxylate

: 133753-34-1,133753-35-2,139489-49-9,139489-50-2
(E)-(2RS,3RS)-2-amino-2,3-methano-4-phosphonobutanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 54.1 percent / CHCl₃ / 70 h / 20 °C / Irradiation

2: 36.3 percent / 6 N HCl / 9 h / Heating

With hydrogenchloride; In chloroform;
DOI:10.1021/jm00109a023