Ethyl 2-cyano-2-fluoro-3-phenylpropanoate

Base Information

Chemical Name:Ethyl 2-cyano-2-fluoro-3-phenylpropanoate
CAS No.:18283-28-8
Molecular Formula:C12H12 F N O2
Molecular Weight:221.231
Hs Code.:
NSC Number:84029
DSSTox Substance ID:DTXSID00292605
Mol file:18283-28-8.mol

Synonyms:18283-28-8;ethyl 2-cyano-2-fluoro-3-phenylpropanoate;NSC84029;NCIOpen2_004708;DTXSID00292605;NSC-84029

Suppliers and Price of Ethyl 2-cyano-2-fluoro-3-phenylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Ethyl 2-cyano-2-fluoro-3-phenylpropanoate

Chemical Property:

Vapor Pressure:0.000178mmHg at 25°C
Boiling Point:329.4°C at 760 mmHg
Flash Point:153°C
Density:1.16g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:221.08520679
Heavy Atom Count:16
Complexity:291

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CC=CC=C1)(C#N)F

Technology Process of Ethyl 2-cyano-2-fluoro-3-phenylpropanoate

There total 1 articles about Ethyl 2-cyano-2-fluoro-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 6731-58-4
ethyl 2-cyano-3-phenylpropanoate

: 18283-28-8
ethyl 2-cyano-2-fluoro-3-phenylpropanoate

Guidance literature:: ethyl 2-cyano-3-phenylpropanoate; With tetra-(n-butyl)ammonium iodide; potassium carbonate; In diethyl ether; water; at 20 ℃; for 0.5h;

With N-fluorobenzene sulfonamide; In diethyl ether; water; at 20 ℃; for 2.5h; Reagent/catalyst;
DOI:10.1080/00397911.2018.1473442