2H-Pyrrole-3,4-diol, 3,4-dihydro-2-(1-hydroxyethyl)-, 1-oxide, [2S-

Base Information

• Chemical Name: 2H-Pyrrole-3,4-diol, 3,4-dihydro-2-(1-hydroxyethyl)-, 1-oxide, [2S-
• CAS No.: 134646-01-8
• Molecular Formula: C6H11NO4
• Molecular Weight: 161.16
• Mol file: 134646-01-8.mol

Synonyms:2H-Pyrrole-3,4-diol, 3,4-dihydro-2-(1-hydroxyethyl)-, 1-oxide, [2S-

Chemical Property of 2H-Pyrrole-3,4-diol, 3,4-dihydro-2-(1-hydroxyethyl)-, 1-oxide, [2S-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2H-Pyrrole-3,4-diol, 3,4-dihydro-2-(1-hydroxyethyl)-, 1-oxide, [2S-

There total 8 articles about 2H-Pyrrole-3,4-diol, 3,4-dihydro-2-(1-hydroxyethyl)-, 1-oxide, [2S- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-deoxy-L-galactose (73-34-7,87-96-7,488-79-9,551-63-3,609-01-8,643-17-4,643-18-5,4164-09-4,6014-42-2,6155-36-8,6189-71-5,6696-41-9,6736-43-2,13224-93-6,22611-09-2,28161-49-1,28161-50-4,28161-52-6,45864-36-6,63814-64-2,71116-59-1,71116-61-5,72598-05-1,87936-88-7,87936-89-8,97466-79-0,116908-82-8,120442-60-6,123484-22-0,133576-32-6) → (2S,3R,4R)-2-((S)-1-Hydroxy-ethyl)-1-oxy-3,4-dihydro-2H-pyrrole-3,4-diol (134646-01-8)

Guidance literature:

Multi-step reaction with 8 steps

1: 0.5M HCl

2: pyridine

3: pyridine

4: (Bu₄N)N₃ / acetonitrile

5: H₂ / 10percent Pd/C

6: dimethyldioxirane / acetone / -78 °C

7: 0.1M BCl₃ / CH₂Cl₂ / -78 °C

8: NaOMe / methanol

With pyridine; hydrogenchloride; hydrogen; sodium methylate; 3,3-dimethyldioxirane; tetrabutylammoniun azide; boron trichloride; palladium on activated charcoal; In methanol; dichloromethane; acetone; acetonitrile;

DOI:10.1016/S0040-4039(00)85979-1

Reference yield:

C21H22O7 (14686-83-0,51236-52-3,51236-57-8,71071-83-5,134645-97-9,135216-51-2,135216-56-7) → (2S,3R,4R)-2-((S)-1-Hydroxy-ethyl)-1-oxy-3,4-dihydro-2H-pyrrole-3,4-diol (134646-01-8)

Guidance literature:

Multi-step reaction with 6 steps

1: pyridine

2: (Bu₄N)N₃ / acetonitrile

3: H₂ / 10percent Pd/C

4: dimethyldioxirane / acetone / -78 °C

5: 0.1M BCl₃ / CH₂Cl₂ / -78 °C

6: NaOMe / methanol

With pyridine; hydrogen; sodium methylate; 3,3-dimethyldioxirane; tetrabutylammoniun azide; boron trichloride; palladium on activated charcoal; In methanol; dichloromethane; acetone; acetonitrile;

DOI:10.1016/S0040-4039(00)85979-1

Reference yield:

C21H21N3O6 → (2S,3R,4R)-2-((S)-1-Hydroxy-ethyl)-1-oxy-3,4-dihydro-2H-pyrrole-3,4-diol (134646-01-8)

Guidance literature:

Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C

2: dimethyldioxirane / acetone / -78 °C

3: 0.1M BCl₃ / CH₂Cl₂ / -78 °C

4: NaOMe / methanol

With hydrogen; sodium methylate; 3,3-dimethyldioxirane; boron trichloride; palladium on activated charcoal; In methanol; dichloromethane; acetone;

DOI:10.1016/S0040-4039(00)85979-1

upstream raw materials:

C₂₀H₁₉NO₆

6-deoxy-L-galactose

C₂₁H₂₃NO₆

C₂₁H₂₂O₇