(S)-2-PHENYL-2-PHENYLAMINO-ETHANOL

Base Information

• Chemical Name: (S)-2-PHENYL-2-PHENYLAMINO-ETHANOL
• CAS No.: 135285-98-2
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.279
• Hs Code.: 2922199090
• Mol file: 135285-98-2.mol

Synonyms:(S)-2-PHENYL-2-PHENYLAMINO-ETHANOL

Chemical Property of (S)-2-PHENYL-2-PHENYLAMINO-ETHANOL

Chemical Property:

• Vapor Pressure: 2.51E-06mmHg at 25°C
• Refractive Index: 1.641
• Boiling Point: 376.2°Cat760mmHg
• PKA: 14.18±0.10(Predicted)
• Flash Point: 146.8°C
• PSA: 32.26000
• Density: 1.156g/cm³
• LogP: 2.90510

Purity/Quality:

96% ^*data from raw suppliers

(2S)-2-phenyl-2-(phenylamino)ethan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-2-PHENYL-2-PHENYLAMINO-ETHANOL

There total 31 articles about (S)-2-PHENYL-2-PHENYLAMINO-ETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

styrene oxide (96-09-3) + aniline (62-53-3) → 2-(phenylamino)-2-phenylethanol (119492-43-2,135285-98-2,13891-02-6)

Guidance literature:

With (tetrabutylammonium)₄ [PW₁₁Fe(H₂O)O₃₉]encapsulated in NH₂-MIL-101(Fe) solid support; In acetonitrile; at 80 ℃; for 1h; under 760.051 Torr; Reagent/catalyst; regioselective reaction;

DOI:10.1039/c7ce00528h

Reference yield: 92.0%

styrene oxide (96-09-3) + aniline (62-53-3) → 1-phenyl-2-phenylaminoethanol (99342-73-1,31121-09-2) + 2-(phenylamino)-2-phenylethanol (119492-43-2,135285-98-2,13891-02-6)

Guidance literature:

With CF₃O₃S^(1-)*C₁₄H₁₄BiO₃⁽¹⁺⁾; In water; at 20 ℃; for 2.5h; regioselective reaction;

DOI:10.1016/j.jorganchem.2010.12.035

Reference yield: 91.0%

iodobenzene (591-50-4) + Phenylglycinol (20989-17-7,56613-80-0,71006-16-1,7568-92-5,188586-38-1) → 2-(phenylamino)-2-phenylethanol (119492-43-2,135285-98-2,13891-02-6)

Guidance literature:

With 2-(diphenylphosphinyl)-benzaldoxime; copper(I) oxide; caesium carbonate; In acetonitrile; at 80 ℃; for 18h;

DOI:10.1016/j.tet.2005.04.053

upstream raw materials:

C₁₄H₁₄BrHgN

styrene oxide

aniline

styrene

Downstream raw materials:

(R)-2-Phenyl-2-(phenylamino)ethanol

Refernces

• 1、 Gupta, Padmini,Garkoti, Charu,Shabir, Javaid,Surabhi,Sah, Digvijay,Mozumdar, Subho. "Amine grafted Fe3O4 immobilized graphene oxide as a recyclable and effectual nanocomposite for the regioselective ring opening reaction". . p. 4013 - 4028. Retrieved 2021/06/25.
• 2、 Ghorbani-Choghamarani, Arash,Taherinia, Zahra. "Synthesis, characterization and catalytic application of Bi2S3 microspheres for Suzuki-Miyaura cross-coupling reaction and chemoselective ring opening of epoxides". . . Retrieved 2020/11/20.