6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline
CAS No.:135631-91-3
Molecular Formula:C11H14BrN^.HCl
Molecular Weight:240.143
Hs Code.:2933499090
European Community (EC) Number:839-077-8
Mol file:135631-91-3.mol

Synonyms:135631-91-3;6-bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline;6-bromo-4,4-dimethyl-2,3-dihydro-1H-quinoline;6-BROMO-4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-QUINOLINE;Quinoline, 6-bromo-1,2,3,4-tetrahydro-4,4-dimethyl-;6-bromo-1,2,3,4-tetrahydro-4,4-dimethylQuinoline;6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline;hydrochloride;SCHEMBL1396642;WBOOAXJWGJAIMB-UHFFFAOYSA-N;MFCD09701997;AKOS024028374;SB33002;SY033774;CS-0279298;EN300-739656;F16236;A849498;4,4-Dimethyl-6-bromo-1,2,3,4-tetrahydroquinoline;6-bromo-4,4-dimethyl-2,3-dihydro-1H-quinoline hydrochloride

Suppliers and Price of 6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Bromo-4,4-Dimethyl-2,3-Dihydro-1h-Quinoline
500mg
$ 310.00

Matrix Scientific
6-Bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride >95%
1g
$ 908.00

Matrix Scientific
6-Bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride >95%
5g
$ 3356.00

Labseeker
6-BROMO-1,2,3,4-TETRAHYDRO-4,4-DIMETHYLQUINOLINEHCL 95
5g
$ 1833.00

J&W Pharmlab
6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline 97%
1g
$ 198.00

J&W Pharmlab
6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline 97%
50mg
$ 95.00

Crysdot
6-Bromo-4,4-dimethyl-2,3-dihydro-1H-quinoline 95+%
1g
$ 268.00

Crysdot
6-Bromo-4,4-dimethyl-2,3-dihydro-1H-quinoline 95+%
5g
$ 760.00

Chemenu
6-Bromo-4,4-dimethyl-2,3-dihydro-1H-quinoline 95%
1g
$ 286.00

Chemenu
6-Bromo-4,4-dimethyl-2,3-dihydro-1H-quinoline 95%
5g
$ 858.00

Total 35 raw suppliers

Chemical Property of 6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Refractive Index:1.542
Boiling Point:338 °C at 760 mmHg
PKA:4.33±0.40(Predicted)
Flash Point:158.2 °C
PSA：12.03000
Density:1.285g/cm³
LogP:3.68030
Storage Temp.:Room temperature.
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:239.03096
Heavy Atom Count:13
Complexity:191

Purity/Quality:

99%, ^*data from raw suppliers

6-Bromo-4,4-Dimethyl-2,3-Dihydro-1h-Quinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CCNC2=C1C=C(C=C2)Br)C

Technology Process of 6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

There total 6 articles about 6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 135631-90-2
4,4-dimethyl-6-bromo-2-oxo-1,2,3,4-tetrahydroquinoline

: 135631-91-3
6-bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran;
DOI:10.1016/S0960-894X(97)00435-6

Reference yield:

: 135631-89-9
N-(3,3'-dimethylacryoloyl)-4-bromoaniline

: 135631-91-3
6-bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / AlCl₃ / a) from 130 deg C to 140 deg C, 1 h, b) 80 deg C, 0.5 h

2: 90 percent / borane-dimethyl sulfide / toluene / a) 0 deg C, 15 min, b) reflux, 5 h

With aluminium trichloride; dimethylsulfide borane complex; In toluene;
DOI:10.1021/jm970196m

Reference yield:

: 3350-78-5
3,3-Dimethylacryloyl chloride

: 135631-91-3
6-bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / CHCl₃ / 5 h / Heating

2: 65 percent / AlCl₃ / a) from 130 deg C to 140 deg C, 1 h, b) 80 deg C, 0.5 h

3: 90 percent / borane-dimethyl sulfide / toluene / a) 0 deg C, 15 min, b) reflux, 5 h

With aluminium trichloride; dimethylsulfide borane complex; In chloroform; toluene;
DOI:10.1021/jm970196m