(S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

Base Information

Chemical Name:(S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
CAS No.:135806-59-6
Molecular Formula:C15H20O4
Molecular Weight:264.32
Hs Code.:2932999099
DSSTox Substance ID:DTXSID20350938
Wikidata:Q82127007
Mol file:135806-59-6.mol

Synonyms:135806-59-6;(S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid;(2S)-6-methoxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid;(S)-6-Methoxy-2,5,7,8-tetramethylchroman-2-carboxylic acid;(2S)-6-methoxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid;SCHEMBL1286094;DTXSID20350938;AKOS022180916;CS-0110150;EN300-7473128;J-006777;J-007302;(S)-6-Methoxy-2,5,7,8-tetramethylchroman-2-carboxylicacid;(S)-Trolox methyl ether, for chiral derivatization, >=98.0%

Suppliers and Price of (S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-Trolox methyl ether for chiral derivatization, ≥98.0%
50mg
$ 166.00

Total 8 raw suppliers

Chemical Property of (S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

Chemical Property:

Vapor Pressure:1.08E-07mmHg at 25°C
Melting Point:143-145 °C
Refractive Index:1.535
Boiling Point:416.8°C at 760 mmHg
PKA:3.31±0.20(Predicted)
Flash Point:152.7°C
PSA：55.76000
Density:1.145g/cm³
LogP:2.57410
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:264.13615911
Heavy Atom Count:19
Complexity:356

Purity/Quality:

NLT 98% ^*data from raw suppliers

(S)-Trolox methyl ether for chiral derivatization, ≥98.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=C(C2=C1OC(CC2)(C)C(=O)O)C)OC)C
Isomeric SMILES:CC1=C(C(=C(C2=C1O[C@](CC2)(C)C(=O)O)C)OC)C

Technology Process of (S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

There total 2 articles about (S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 139658-02-9
3-O-<(S)-3,4-Dihydro-6-methoxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-ylcarbonyl>-1,2-O-isopropyliden-α-D-glucofuranose

: 135806-59-6,139658-04-1
(S)-Trolox-methylether

Guidance literature:: With potassium hydroxide; In methanol; for 2h; Heating;

Reference yield:

: 139657-99-1,139658-00-7
3-O-<(RS)-3,4-Dihydro-6-methoxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-ylcarbonyl>-1,2:5,6-di-O-isopropyliden-α-D-glucofuranose

: 135806-59-6,139658-04-1
(S)-Trolox-methylether

Guidance literature:: Multi-step reaction with 2 steps

1: 34 percent / HOAc / methanol; H₂O / 96 h / 50 °C

2: 94 percent / KOH / methanol / 2 h / Heating

With potassium hydroxide; acetic acid; In methanol; water;