(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene

Base Information

Chemical Name:(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene
CAS No.:136705-64-1
Molecular Formula:C22H36P2
Molecular Weight:362.475
Hs Code.:29310099
European Community (EC) Number:635-217-5
UNII:7N2EB15PAQ
DSSTox Substance ID:DTXSID30159893
Nikkaji Number:J1.552.819B
Wikidata:Q27268588
Mol file:136705-64-1.mol

Synonyms:136705-64-1;(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene;(R,R)-Ethyl-DUPHOS;Ethyl-duphos, (R,R)-;(-)-Duphos;(R,R)-Et-DuPHOS;(R,R)-Et-duphos [MI];1,2-Bis((2R,5R)-2,5-diethylphospholan-1-yl)benzene;UNII-7N2EB15PAQ;7N2EB15PAQ;(-)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene;(2R,5R)-1-[2-[(2R,5R)-2,5-diethylphospholan-1-yl]phenyl]-2,5-diethylphospholane;Phospholane, 1,1'-(1,2-phenylene)bis[2,5-diethyl-, (2R,2'R,5R,5'R)-;Phospholane, 1,1'-(1,2-phenylene)bis(2,5-diethyl-, (2R,2'R,5R,5'R)-;MFCD00142335;(R,R)-EtDuPHOS;SCHEMBL789221;DTXSID30159893;CS-0092887;D75367;J-006889;Q27268588;(-)-1,2-Bis-[(2R,5R)-2,5-diethylphospholano]-benzene (R,R-Et-Duphos);(-)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene, kanata purity;(-)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene, technical, ~90% (GC)

Suppliers and Price of (-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Strem Chemicals
(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene, 98+% (R,R)-Et-DUPHOS
2g
$ 819.00

Strem Chemicals
(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene, 98+% (R,R)-Et-DUPHOS
500mg
$ 252.00

Strem Chemicals
(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene, 98+% (R,R)-Et-DUPHOS
100mg
$ 72.00

Sigma-Aldrich
(?)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene kanata purity
100mg
$ 76.90

Sigma-Aldrich
(?)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene technical,~90%(GC)
100 mg
$ 220.00

Sigma-Aldrich
(?)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene technical, ~90% (GC)
100mg-f
$ 213.00

Sigma-Aldrich
(?)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene kanata purity
500mg
$ 278.00

ChemScene
(R,R)-EtDuPHOS >97.0%
250mg
$ 250.00

ChemScene
(R,R)-EtDuPHOS >97.0%
100mg
$ 125.00

Biosynth Carbosynth
(?)-1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene
500 mg
$ 675.00

Total 16 raw suppliers

Chemical Property of (-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene

Chemical Property:

Vapor Pressure:1.67E-08mmHg at 25°C
Refractive Index:n 20/D 1.6
Boiling Point:468.5°C at 760 mmHg
Flash Point:>230 °F
PSA：27.18000
Density:1.01 g/mL at 25 °C
LogP:6.60300
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Air Sensitive
XLogP3:5.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:6
Exact Mass:362.22922514
Heavy Atom Count:24
Complexity:322

Purity/Quality:

99%, ^*data from raw suppliers

(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene, 98+% (R,R)-Et-DUPHOS ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1CCC(P1C2=CC=CC=C2P3C(CCC3CC)CC)CC
Isomeric SMILES:CC[C@@H]1CC[C@H](P1C2=CC=CC=C2P3[C@@H](CC[C@H]3CC)CC)CC
Uses Catalyst for asymmetric hydrogenations. DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

Technology Process of (-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene

There total 2 articles about (-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 136705-66-3
(3S,6S)-octane-3,6-diol

: 136705-64-1
1,2-bis((2R,5R)-2,5-diethylphosphoranylidene)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) SOCl₂, 2.) RuCl₃*3H₂O, NaIO₄ / 1.) CCl₄, reflux, 1.5 h, 2.) CCl₄, CH₃CN, H₂O, 25 deg C, 1 h

2: 1.) n-BuLi, 3.) n-BuLi

With ruthenium trichloride; sodium periodate; n-butyllithium; thionyl chloride;

Reference yield:

: 80510-04-9
1,2-bis(phosphino)benzene

: 136705-67-4
(S,S)-octane-3,6-diol cyclic sulfate

: 136705-64-1
1,2-bis((2R,5R)-2,5-diethylphosphoranylidene)benzene

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction;

Reference yield: 97.0%

: tetrafluoroboric acid diethyletherate

: acetylacetonato(1,5-cyclooctadiene)rhodium(I)

: 136705-64-1
1,2-bis((2R,5R)-2,5-diethylphosphoranylidene)benzene

: (-)-1,2-bis-[(2R,5R)-2,5-diethylphospholano]benzene(cyclooctadiene)rhodium(I) tetrafluoroborate

Guidance literature:: tetrafluoroboric acid diethyletherate; acetylacetonato(1,5-cyclooctadiene)rhodium(I); In tetrahydrofuran; tert-butyl methyl ether; isopropyl alcohol; at 55 ℃; for 0.5h;

1,2-bis((2R,5R)-2,5-diethylphosphoranylidene)benzene; In tetrahydrofuran; tert-butyl methyl ether; isopropyl alcohol; at 55 ℃; for 0.5h;