1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol

Base Information

Chemical Name:1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol
CAS No.:136770-76-8
Molecular Formula:C19H41NO2
Molecular Weight:315.53
Hs Code.:
DSSTox Substance ID:DTXSID90438358
Nikkaji Number:J1.698.152D
Wikidata:Q27147847
Mol file:136770-76-8.mol

Synonyms:1-O-hexadecyl-2-desoxy-2-amino-sn-glycerol;1-O-hexadecyl-2-desoxy-2-aminoglycerol

Suppliers and Price of 1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol
25mg
$ 105.00

Total 2 raw suppliers

Chemical Property of 1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol

Chemical Property:

PSA：55.48000
LogP:5.50420
Storage Temp.:-15°C
XLogP3:6.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:18
Exact Mass:315.313729551
Heavy Atom Count:22
Complexity:200

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCCOCC(CO)N
Isomeric SMILES:CCCCCCCCCCCCCCCCOC[C@H](CO)N
Uses 1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol is a substrate for human sphingosine kinase.

Technology Process of 1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol

There total 7 articles about 1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1353577-11-3
(R)-4-(hexadecyloxymethyl)-3-oxazolidin-2-one

: 136770-76-8,151312-95-7
1-O-hexadecyl-2-amino-2-deoxy-sn-glycerol

Guidance literature:: With lithium hydroxide monohydrate; In ethanol; for 1h; Reflux;
DOI:10.1016/j.tetasy.2011.11.002

Reference yield:

: 20779-14-0
methanesulfonic acid hexadecyl ester

: 136770-76-8,151312-95-7
1-O-hexadecyl-2-amino-2-deoxy-sn-glycerol

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran / 20 - 50 °C

1.2: tetrahydrofuran / 12 h / Heating

2.1: BF₃; MeOH / 20 °C

With methanol; boron trifluoride; sodium hydride; In tetrahydrofuran; 1.1: deprotonation / 1.2: Etherification / 2.1: detritylation;
DOI:10.1016/S0009-3084(00)00156-0