D-threo-Pentose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI)

Base Information

• Chemical Name: D-threo-Pentose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI)
• CAS No.: 137553-93-6
• Molecular Formula: C8H14O3
• Molecular Weight: 158.2
• Mol file: 137553-93-6.mol

Synonyms:D-threo-Pentose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI)

Chemical Property of D-threo-Pentose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI)

Chemical Property:

• PSA: 35.53000
• LogP: 1.11540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D-threo-Pentose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI)

There total 8 articles about D-threo-Pentose, 4,5-dideoxy-2,3-O-(1-methylethylidene)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Trifluoro-acetic acid ((4S,5R)-5-ethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-p-tolylsulfanyl-methyl ester (633317-88-1) → (4S,5R)-5-Ethyl-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde (137553-93-6)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; at 0 - 20 ℃; for 0.25h;

DOI:10.1016/j.tetlet.2003.09.082

Reference yield:

(4S,5R)-5-Ethyl-2,2-dimethyl-1,3-dioxolan-4-carbonsaeure-ethylester (85994-57-6) → (4S,5R)-5-Ethyl-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde (137553-93-6)

Guidance literature:

(4S,5R)-5-Ethyl-2,2-dimethyl-1,3-dioxolan-4-carbonsaeure-ethylester; With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃; for 3h;

With methanol; In hexane; dichloromethane; for 0.25h;

DOI:10.1016/j.tetasy.2009.11.018

Reference yield:

1-((4R,5R)-5-Ethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethane-1,2-diol → (4S,5R)-5-Ethyl-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde (137553-93-6)

Guidance literature:

With sodium periodate; In water; acetone; phosphate buffer pH 7;

DOI:10.1016/S0040-4039(00)93473-7

upstream raw materials:

Trifluoro-acetic acid ((4S,5R)-5-ethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-p-tolylsulfanyl-methyl ester

(2S,3R)-1-((S)-Toluene-4-sulfinyl)-pentane-2,3-diol

(4R,5S)-4-Ethyl-2,2-dimethyl-5-((S)-toluene-4-sulfinylmethyl)-[1,3]dioxolane

5,6-dideoxy-D-threo-hex-2-ulose