12H-QUINO[2,3-B][1,5] BENZO DIAZEPIN-12-ONE, 5,11-DIHYDRO-

Base Information

• Chemical Name: 12H-QUINO[2,3-B][1,5] BENZO DIAZEPIN-12-ONE, 5,11-DIHYDRO-
• CAS No.: 137612-86-3
• Molecular Formula: C16H11N3O
• Molecular Weight: 261.28
• Mol file: 137612-86-3.mol

Synonyms:12H-QUINO[2,3-B][1,5] BENZO DIAZEPIN-12-ONE, 5,11-DIHYDRO-

Chemical Property of 12H-QUINO[2,3-B][1,5] BENZO DIAZEPIN-12-ONE, 5,11-DIHYDRO-

Chemical Property:

• PSA: 61.54000
• LogP: 3.11980

Purity/Quality:

97% ^*data from raw suppliers

5,11-DIHYDRO-12H-QUINO[2,3-B][1,5]BENZO DIAZEPIN-12-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 12H-QUINO[2,3-B][1,5] BENZO DIAZEPIN-12-ONE, 5,11-DIHYDRO-

There total 2 articles about 12H-QUINO[2,3-B][1,5] BENZO DIAZEPIN-12-ONE, 5,11-DIHYDRO- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-chloro-3-quinolinecarboxylic acid (73776-25-7) + 1,2-diamino-benzene (95-54-5) → quino<2,3-b><1,5>benzodiazepin-12-one (137612-86-3)

Guidance literature:

In xylene; at 130 - 135 ℃; for 2h;

Reference yield:

2-chloro-3-quinoline carboxaldehyde (73568-25-9) → quino<2,3-b><1,5>benzodiazepin-12-one (137612-86-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / AgNO₃, NaOH / ethanol / 4 h / Ambient temperature

2: 72 percent / xylene / 2 h / 130 - 135 °C

With sodium hydroxide; silver nitrate; In ethanol; xylene;

upstream raw materials:

2-chloro-3-quinolinecarboxylic acid

1,2-diamino-benzene

2-chloro-3-quinoline carboxaldehyde

Refernces