L-693,403 MALEATE

Base Information

• Chemical Name: L-693,403 MALEATE
• CAS No.: 137730-52-0
• Molecular Formula: C24H27NO4
• Molecular Weight: 277.409
• Hs Code.: 2933399090
• Mol file: 137730-52-0.mol

Synonyms:N-1'-BENZYL-3,4-DIHYDROSPIRO[1H-INDENE-1,4'-PIPERIDINE] MALEATE;L-693,403 MALEATE

Chemical Property of L-693,403 MALEATE

Chemical Property:

• Vapor Pressure: 4.98E-15mmHg at 25°C
• Refractive Index: ">
• Boiling Point: 595.5°Cat760mmHg
• PKA: 9.09±0.20(Predicted)
• Flash Point: 314°C
• PSA: 77.84000
• Density: g/cm³
• LogP: 3.81630
• Storage Temp.: Desiccate at -20°C

Purity/Quality:

97% ^*data from raw suppliers

L-693,403maleate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-693,403 Maleate is a sigma receptor-binding compound used for treatment of diabetes-associated pain.

Technology Process of L-693,403 MALEATE

There total 8 articles about L-693,403 MALEATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

→ 1'-Benzyl-2,3-Dihydrospiro[indene-1,4'-piperidine] (137730-52-0) + N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine (118753-70-1)

Guidance literature:

Reference yield: 70.0%

→ 1'-Benzyl-2,3-Dihydrospiro[indene-1,4'-piperidine] (137730-52-0)

Guidance literature:

Reference yield: 32.0%

1-benzyl-4-(2-phenylethyl)-1,2,3,6-tetrahydropyridine (38025-43-3) → 1'-Benzyl-2,3-Dihydrospiro[indene-1,4'-piperidine] (137730-52-0)

Guidance literature:

With phosphoric acid; for 80h; Heating;

upstream raw materials:

1-benzyl-4-(2-phenylethyl)-1,2,3,6-tetrahydropyridine

2,3-dihydrospiro[1H-indene-1,4'-piperidine]

benzyl bromide

4-(2-phenylethyl)pyridine