1-Cyclohexyl-2-fluoropentan-1-one

Base Information

Chemical Name:1-Cyclohexyl-2-fluoropentan-1-one
CAS No.:138042-74-7
Molecular Formula:C11H19FO
Molecular Weight:186.27
Hs Code.:
DSSTox Substance ID:DTXSID00567481
Nikkaji Number:J498.553B
Mol file:138042-74-7.mol

Synonyms:138042-74-7;1-Cyclohexyl-2-fluoropentan-1-one;1-CYCLOHEXYL-2-FLUORO-1-PENTANONE;1-Pentanone, 1-cyclohexyl-2-fluoro- (9CI);DTXSID00567481

Suppliers and Price of 1-Cyclohexyl-2-fluoropentan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Cyclohexyl-2-fluoropentan-1-one

Chemical Property:

PSA：17.07000
LogP:3.27400
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:186.141993387
Heavy Atom Count:13
Complexity:162

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC(C(=O)C1CCCCC1)F

Technology Process of 1-Cyclohexyl-2-fluoropentan-1-one

There total 5 articles about 1-Cyclohexyl-2-fluoropentan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 138042-64-5
1-cyclohexyl-2-fluoro-2-(phenylsulfinyl)-1-pentanone

: 138042-74-7
1-cyclohexyl-2-fluoro-1-pentanone

Guidance literature:: With ethylmagnesium bromide; In diethyl ether; at -78 ℃; for 0.0833333h;
DOI:10.1246/bcsj.65.2800

Reference yield:

: 138042-53-2
2-Benzenesulfinyl-1-cyclohexyl-2-fluoro-pentan-1-ol

: 138042-74-7
1-cyclohexyl-2-fluoro-1-pentanone

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride, dimethyl sulfoxide / CH₂Cl₂ / 0.25 h / -60 °C

2: 85 percent / EtMgBr / diethyl ether / 0.08 h / -78 °C

With oxalyl dichloride; ethylmagnesium bromide; dimethyl sulfoxide; In diethyl ether; dichloromethane;
DOI:10.1246/bcsj.65.2800

Reference yield:

: 2043-61-0
cyclohexanecarbaldehyde

: 138042-74-7
1-cyclohexyl-2-fluoro-1-pentanone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, -78 deg C, 10 min, 2.) THF, -78 deg C, 5 min

2: oxalyl chloride, dimethyl sulfoxide / CH₂Cl₂ / 0.25 h / -60 °C

3: 85 percent / EtMgBr / diethyl ether / 0.08 h / -78 °C

With oxalyl dichloride; ethylmagnesium bromide; dimethyl sulfoxide; lithium diisopropyl amide; In diethyl ether; dichloromethane;
DOI:10.1246/bcsj.65.2800