Technology Process of Cyclobutanecarboxylic acid, 2-(1-methylethenyl)-, methyl ester, (1R-trans)-
There total 5 articles about Cyclobutanecarboxylic acid, 2-(1-methylethenyl)-, methyl ester, (1R-trans)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium diisopropyl amide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane;
at -70 ℃;
for 1h;
- Guidance literature:
-
With
disodium hydrogenphosphate; sodium amalgam;
In
methanol;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1007/s12272-011-0904-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 10 h / Inert atmosphere; Reflux
2: tetrakis(triphenylphosphine) palladium(0) / dimethyl sulfoxide / 3 h / 20 °C / Inert atmosphere
3: sodium amalgam; disodium hydrogenphosphate / methanol / 2 h / 20 °C / Inert atmosphere
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; disodium hydrogenphosphate; sodium amalgam; tetrakis(triphenylphosphine) palladium(0);
In
methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1007/s12272-011-0904-7
