Isoquinoline-5,6-diamine

Base Information

Chemical Name:Isoquinoline-5,6-diamine
CAS No.:140192-89-8
Molecular Formula:C₉H₉N₃
Molecular Weight:159.191
Hs Code.:
ChEMBL ID:CHEMBL27753
DSSTox Substance ID:DTXSID60567381
Nikkaji Number:J2.020.411G
Wikidata:Q82453257
Mol file:140192-89-8.mol

Synonyms:Isoquinoline-5,6-diamine;140192-89-8;5,6-ISOQUINOLINEDIAMINE;CHEMBL27753;DTXSID60567381;BDBM50126274

Suppliers and Price of Isoquinoline-5,6-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Isoquinoline-5,6-diamine
250mg
$ 835.00

AccelPharmtech
5,6-Isoquinolinediamine 97.00%
25G
$ 5120.00

AccelPharmtech
5,6-Isoquinolinediamine 97.00%
5G
$ 2750.00

AccelPharmtech
5,6-Isoquinolinediamine 97.00%
1G
$ 2370.00

Total 1 raw suppliers

Chemical Property of Isoquinoline-5,6-diamine

Chemical Property:

PSA：64.93000
LogP:2.56160
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:159.079647300
Heavy Atom Count:12
Complexity:160

Purity/Quality:: Isoquinoline-5,6-diamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C2=C1C=NC=C2)N)N
Uses Isoquinoline-5,6-diamine is a useful intermediate.

Technology Process of Isoquinoline-5,6-diamine

There total 8 articles about Isoquinoline-5,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 140192-88-7
5-amino-6-nitroisoquinoline

: 140192-89-8
5,6-diaminoisoquinoline

Guidance literature:: With nickel; hydrazine hydrate; In ethanol; for 6h; Heating;

Reference yield:

: 27461-33-2
N-(isoquinolin-5-yl)acetamide

: 140192-89-8
5,6-diaminoisoquinoline

Guidance literature:: Multi-step reaction with 4 steps

1: NBS / dimethylformamide

2: HNO₃; H₂SO₄

3: HCl / ethanol

4: H₂ / Pd/C

With hydrogenchloride; N-Bromosuccinimide; sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00107-0

Reference yield:

: 1125-60-6
isoquinolin-5-ylamine

: 140192-89-8
5,6-diaminoisoquinoline

Guidance literature:: Multi-step reaction with 5 steps

1: NBS / dimethylformamide

2: HNO₃; H₂SO₄

3: HCl / ethanol

4: H₂ / Pd/C

With hydrogenchloride; N-Bromosuccinimide; sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00107-0